Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Inbred strain variation in contextual and cued fear conditioning behavior
Autore:
Bolivar, VJ; Pooler, O; Flaherty, L;
Indirizzi:
SUNY Albany, Genomics Inst, Wadsworth Ctr, Albany, NY 12201 USA SUNY Albany Albany NY USA 12201 Inst, Wadsworth Ctr, Albany, NY 12201 USA SUNY Albany, Dept Biomed Sci, Albany, NY 12201 USA SUNY Albany Albany NY USA 12201 ny, Dept Biomed Sci, Albany, NY 12201 USA
Titolo Testata:
MAMMALIAN GENOME
fascicolo: 8, volume: 12, anno: 2001,
pagine: 651 - 656
SICI:
0938-8990(200108)12:8<651:ISVICA>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
TRAIT LOCUS ANALYSIS; ELECTROLYTIC LESIONS; BASOLATERAL AMYGDALA; POTENTIATED STARTLE; FREEZING BEHAVIOR; MICE; RATS; HIPPOCAMPUS; MEMORY; ACQUISITION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Flaherty, L SUNY Albany, Genomics Inst, Wadsworth Ctr, 120 New Scotland Ave,POB 22002,Albany, NY 12201 USA SUNY Albany 120 New Scotland Ave,POB 22002Albany NY USA 12201
Citazione:
V.J. Bolivar et al., "Inbred strain variation in contextual and cued fear conditioning behavior", MAMM GENOME, 12(8), 2001, pp. 651-656

Abstract

A number of commonly used inbred strains were surveyed in a fear-conditioning paradigm conducted with an automated computer-controlled system. Control studies were used to verify the automated system. Response to shock was also monitored to determine if it was associated with contextual and/or cuedconditioning behavior. After three pairings of tone with shock, fear conditioning was measured 24 h later in 129S1/SvImJ (129), A/J (A), BALB/cByJ (BALB), C3H/HeJ (C3H), C57BL/6J (B6), CBA/J (CBA), DBA/2J (D2), and FVB/NJ (FVB) male and female mice. There were both significant strain acid sex differences in response. To determine the effects of vision on this behavior, C3H mice (with retinal degeneration) were compared with C3.BLiA-+(Pdc6b) congenics (withoul retinal degeneration). Here, vision was Found to pl:ly a minimal role in responsiveness in this paradigm. Because this fear-conditioning test is;automated, it can be used for the rapid screening of ii large number of mice, such as required fur mutagenesis studies.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 08:54:12