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Titolo:
Adjustment of incidence rates after an estimate of completeness and accuracy in registration of acute leukemias in a Swedish population
Autore:
Astrom, M; Bodin, L; Tidefelt, U;
Indirizzi:
Orebro Med Ctr Hosp, Dept Internal Med, Div Hematol, S-70185 Orebro, Sweden Orebro Med Ctr Hosp Orebro Sweden S-70185 ematol, S-70185 Orebro, Sweden
Titolo Testata:
LEUKEMIA & LYMPHOMA
fascicolo: 5-6, volume: 41, anno: 2001,
pagine: 559 - 570
SICI:
1042-8194(200105)41:5-6<559:AOIRAA>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACUTE MYELOID-LEUKEMIA; ACUTE LYMPHOBLASTIC-LEUKEMIA; CANCER REGISTRATION; DEATH CERTIFICATES; REGISTER; EPIDEMIOLOGY; REMISSION; QUALITY;
Keywords:
acute leukemia; AML; ALL; incidence; registration; selection bias;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
28
Recensione:
Indirizzi per estratti:
Indirizzo: Astrom, M Orebro Med Ctr Hosp, Dept Internal Med, Div Hematol, S-70185 Orebro, Sweden Orebro Med Ctr Hosp Orebro Sweden S-70185 70185 Orebro, Sweden
Citazione:
M. Astrom et al., "Adjustment of incidence rates after an estimate of completeness and accuracy in registration of acute leukemias in a Swedish population", LEUK LYMPH, 41(5-6), 2001, pp. 559-570

Abstract

Earlier studies have revealed undernotification of hematological malignancies in Swedish and other Cancer Registries. We present epidemiological dataon AML, ALL and unspecified AL in adults diagnosed 1987-1992 in a well-defined population, Blast crises of CML were excluded. The Swedish Cancer Registry and Cause of Death Registry were compared and patient records reviewedfor validation. When available, listings of pathology bone marrow reports and inpatient discharge diagnoses were utilized for casefinding. 260 cases of acute leukemias could be verified in a population of 663,135 adults, corresponding to a yearly incidence of 6.5/100,000. The median age of the patients was 69.2 years, 214 cases were AML, 38 ALL and eight unspecified AL. Undernotification in the Cancer Registry was found to be 15.4%, greater for AML and unspecified AL than for ALL. In addition the coding was not uniform, resulting in an incidence rate in adults of 5.3/100,000 for the Cancer Registry which is 18.5% lower than that of our study. A significant survival advantage was seen for notified patients. Combination of the Cancer Registry and Cause of Death Registry gave acceptable coverage, omitting only four patients. As the incidence of acute leukemias in our study is comparativelyhigh, we hypothesize that underestimation of incidence and overestimation of survival are general problems for cancer registries.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/04/20 alle ore 10:47:58