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Titolo:
Ion pump sorting in polarized renal epithelial cells
Autore:
Caplan, MJ;
Indirizzi:
Yale Univ, Sch Med, Dept Cellular & Mol Physiol, New Haven, CT 06510 USA Yale Univ New Haven CT USA 06510 r & Mol Physiol, New Haven, CT 06510 USA
Titolo Testata:
KIDNEY INTERNATIONAL
fascicolo: 2, volume: 60, anno: 2001,
pagine: 427 - 430
SICI:
0085-2538(200108)60:2<427:IPSIPR>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
GASTRIC-ACID SECRETION; PLASMA-MEMBRANE; DISTAL COLON; LOCALIZATION; H+,K+-ATPASE; H,K-ATPASE; PROTEIN; KIDNEY; ATPASE; SEQUENCE;
Keywords:
Na,K-ATPase; H,K-ATPase; cell polarity; sorting; protein transport; solute and fluid transport; tight junction;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: Caplan, MJ Yale Univ, Sch Med, Dept Cellular & Mol Physiol, 333 Cedar St, New Haven, CT 06510 USA Yale Univ 333 Cedar St New Haven CT USA 06510 ven, CT 06510 USA
Citazione:
M.J. Caplan, "Ion pump sorting in polarized renal epithelial cells", KIDNEY INT, 60(2), 2001, pp. 427-430

Abstract

The plasma membranes of renal epithelial cells are divided into distinct apical and basolateral domains, which contain different inventories of ion transport proteins. Without this polarity vectorial ion and fluid transport would not be possible. Little is known of the signals and mechanisms that renal epithelial cells use to establish and maintain polarized distributionsof their ion transport proteins. Analysis of ion pump sorting reveals thatmultiple complex signals participate in determining and regulating these proteins' subcellular localizations.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 15:33:16