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Titolo:
Tetramerization is a conserved feature of the virion-associated protein inplant pararetroviruses
Autore:
Stavolone, L; Herzog, E; Leclerc, D; Hohn, T;
Indirizzi:
Friedrich Miescher Inst, CH-4002 Basel, Switzerland Friedrich Miescher Inst Basel Switzerland CH-4002 002 Basel, Switzerland
Titolo Testata:
JOURNAL OF VIROLOGY
fascicolo: 16, volume: 75, anno: 2001,
pagine: 7739 - 7743
SICI:
0022-538X(200108)75:16<7739:TIACFO>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
CAULIFLOWER MOSAIC-VIRUS; READING FRAME-III; COILED-COIL; BINDING ACTIVITY; PRODUCT; SEQUENCES; DOMAIN; FORMS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
33
Recensione:
Indirizzi per estratti:
Indirizzo: Hohn, T Friedrich Miescher Inst, POB 2543, CH-4002 Basel, Switzerland Friedrich Miescher Inst POB 2543 Basel Switzerland CH-4002 erland
Citazione:
L. Stavolone et al., "Tetramerization is a conserved feature of the virion-associated protein inplant pararetroviruses", J VIROLOGY, 75(16), 2001, pp. 7739-7743

Abstract

All plant pararetroviruses belong to the Caulimoviridae family. This family contains six genera of viruses with different biological, serological, and molecular characteristics. Although some important mechanisms of viral replication and host infection are understood, much remains to be discovered about the many functions of the viral proteins. The focus of this study, the virion-associated protein (VAP), is conserved among all members of the group and contains a coiled-coil structure that has been shown to assemble asa tetramer in the case of cauliflower mosaic virus. We have used the yeasttwo-hybrid system to characterize self-association of the VAPs of four distinct plant pararetroviruses, each belonging to a different genus of Caulimoviridae. Chemical cross-linking confirmed that VAPs assemble into tetramers. Tetramerization is thus a common property of these proteins in plant pararetroviruses. The possible implications of this conserved feature for VAP function are discussed.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 00:20:18