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Titolo:
The pharmacology and toxicology of atypical antipsychotic agents
Autore:
Burns, MJ;
Indirizzi:
Beth Israel Deaconess Med Ctr, Dept Emergency Med, Div Toxicol, Boston, MA02215 USA Beth Israel Deaconess Med Ctr Boston MA USA 02215 ol, Boston, MA02215 USA
Titolo Testata:
JOURNAL OF TOXICOLOGY-CLINICAL TOXICOLOGY
fascicolo: 1, volume: 39, anno: 2001,
pagine: 1 - 14
SICI:
0731-3810(2001)39:1<1:TPATOA>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
NEUROLEPTIC MALIGNANT SYNDROME; DRUG-DRUG INTERACTIONS; OLANZAPINE OVERDOSE; RISPERIDONE OVERDOSE; EXTRAPYRAMIDAL SYMPTOMS; INDUCED AGRANULOCYTOSIS; CLOZAPINE INTOXICATION; PLASMA-CONCENTRATION; SERUM CONCENTRATIONS; SCHIZOPHRENIA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
115
Recensione:
Indirizzi per estratti:
Indirizzo: Burns, MJ Beth Israel Deaconess Med Ctr, Dept Emergency Med, Div Toxicol, 330 Brookline Ave, Boston, MA 02215 USA Beth Israel Deaconess Med Ctr 330 Brookline Ave Boston MA USA 02215
Citazione:
M.J. Burns, "The pharmacology and toxicology of atypical antipsychotic agents", J TOX-CLIN, 39(1), 2001, pp. 1-14

Abstract

Recently atypical antipsychotic agents have largely replaced traditional agents as first-line drugs for the treatment of schizophrenia. It is likely that atypical agents will soon account for the majority of poisonings from antipsychotic agents that present to health care facilities in the US. Thisarticle reviews the pharmacodynamics, pharmacokinetics, and toxicology of atypical antipsychotic drugs, chiefly clozapine, risperidone, olanzapine, and quetiapine. A descriptive summary of the human overdose experience with these agents is provided. Adverse effect and drug interaction data are reviewed. Based on the available pharmacodynamic, pharmacokinetic, and human over-dose data, recommendations on management are provided.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/20 alle ore 16:17:41