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Titolo:
Serotonin 2A receptor gene polymorphism is not associated with completed suicide
Autore:
Ono, H; Shirakawa, O; Nishiguchi, N; Nishimura, A; Nushida, H; Ueno, Y; Maeda, K;
Indirizzi:
Kobe Univ, Sch Med, Dept Neurol & Psychiat, Kobe, Hyogo 650, Japan Kobe Univ Kobe Hyogo Japan 650 Neurol & Psychiat, Kobe, Hyogo 650, Japan Shiga Univ Med Sci, Dept Legal Med, Otsu, Shiga 52021, Japan Shiga Univ Med Sci Otsu Shiga Japan 52021 l Med, Otsu, Shiga 52021, Japan Kobe Univ, Sch Med, Dept Legal Med, Kobe, Hyogo 650, Japan Kobe Univ KobeHyogo Japan 650 ed, Dept Legal Med, Kobe, Hyogo 650, Japan
Titolo Testata:
JOURNAL OF PSYCHIATRIC RESEARCH
fascicolo: 3, volume: 35, anno: 2001,
pagine: 173 - 176
SICI:
0022-3956(200105/06)35:3<173:S2RGPI>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
T102C POLYMORPHISM; CEREBROSPINAL-FLUID; SCHIZOPHRENIA; PROMOTER; 5-HT2A; IDENTIFICATION; FENFLURAMINE; LETHALITY; DISORDERS; IDEATION;
Keywords:
suicide; completed suicide; genetics; serotonin 2A receptor gene; polymorphism; association study;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Clinical Medicine
Life Sciences
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Shirakawa, O Kobe Univ, Sch Med, Dept Neurol & Psychiat, Kobe, Hyogo 650, Japan Kobe Univ Kobe Hyogo Japan 650 chiat, Kobe, Hyogo 650, Japan
Citazione:
H. Ono et al., "Serotonin 2A receptor gene polymorphism is not associated with completed suicide", J PSYCH RES, 35(3), 2001, pp. 173-176

Abstract

Several lines of evidence indicate that a serotonergic dysfunction is involved in the biological susceptibility to suicide. Recently, the A-1438G polymorphism of the serotonin 2A (5-HT2A) receptor gene has been suggested to be associated with suicide, but the results are inconsistent. We examined whether the A-1438G polymorphism of the 5-HT2A receptor gene was associated with suicide itself using 151 Japanese completed suicides. No significant difference in genotype distribution or allele frequencies of the polymorphism was found between the completed suicides and the comparison group. We conclude that the A-1438G polymorphism of the 5-HT2A receptor gene is not likely to have a major effect on the biological susceptibility of suicide. (C) 2001 Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/09/20 alle ore 06:23:30