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Titolo:
EFFECTS OF SYMPATHECTOMY ON ENDOTHELIN-1 AND HISTAMINE RESPONSES OF RABBIT CAROTID-ARTERY
Autore:
UTKAN T; KAYA T; SARIOGLU Y;
Indirizzi:
AKASYALAR CAD A23 BLOK,DAIRE 15 KOCAELI TURKEY CUMHURIYET UNIV,FAC MED,DEPT PHARMACOL SIVAS TURKEY
Titolo Testata:
General pharmacology
fascicolo: 2, volume: 29, anno: 1997,
pagine: 197 - 199
SICI:
0306-3623(1997)29:2<197:EOSOEA>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
EXPERIMENTAL SUBARACHNOID HEMORRHAGE; CEREBRAL-ARTERIES; EAR ARTERY; DENERVATION; RELAXATION; CELLS;
Keywords:
SYMPATHECTOMY; ENDOTHELIN-1; HISTAMINE; CAROTID ARTERY; RABBIT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
21
Recensione:
Indirizzi per estratti:
Citazione:
T. Utkan et al., "EFFECTS OF SYMPATHECTOMY ON ENDOTHELIN-1 AND HISTAMINE RESPONSES OF RABBIT CAROTID-ARTERY", General pharmacology, 29(2), 1997, pp. 197-199

Abstract

1. The effects of chronic sympathectomy on contractile responses of rabbit common carotid artery was studied in vitro. 2. Endothelin-1 (ET-I), histamine, KCl and papaverine concentration-response curves of sympathectomized and sham-operated (control) Vessels were recorded and analyzed. Effects of endothelium removal also were investigated. 3. The contractions elicited by ET-1 and histamine in sympathectomized preparations did not change when compared with controls. Papaverine, which produces endothelium-independent relaxation, and KCI, which produces endothelium-independent contraction, did not differ from controls. No significant difference was observed between the contractile responses ofsympathectomized vessels and those of control vessels to ET-1 and histamine after the removal of endothelium. 4. These results indicate that chronic sympathectomy did not affect the sensitivity to exogenous ET-1 and histamine of the vascular smooth muscle. GEN PHARMAC 29;2:197-199, 1997. (C) 1997 Elsevier Science Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/12/20 alle ore 18:10:08