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Titolo:
Relation between depression after stroke, antidepressant therapy, and functional recovery
Autore:
Gainotti, G; Antonucci, G; Marra, C; Paolucci, S;
Indirizzi:
Catholic Univ Sacred Heart, Neuropsychol Unit, I-00168 Rome, Italy Catholic Univ Sacred Heart Rome Italy I-00168 Unit, I-00168 Rome, Italy Univ La Sapienza, Dept Psychol, Rome, Italy Univ La Sapienza Rome ItalyUniv La Sapienza, Dept Psychol, Rome, Italy IRCC Santa Lucia, Rome, Italy IRCC Santa Lucia Rome ItalyIRCC Santa Lucia, Rome, Italy
Titolo Testata:
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
fascicolo: 2, volume: 71, anno: 2001,
pagine: 258 - 261
SICI:
0022-3050(200108)71:2<258:RBDASA>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSTSTROKE DEPRESSION; MOOD DISORDERS; SCALE; REHABILITATION;
Keywords:
poststroke depression; antidepressant drugs; functional recovery;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
19
Recensione:
Indirizzi per estratti:
Indirizzo: Gainotti, G Catholic Univ Sacred Heart, Neuropsychol Unit, L go A Gemelli 8, I-00168 Rome, Italy Catholic Univ Sacred Heart L go A Gemelli 8 Rome Italy I-00168
Citazione:
G. Gainotti et al., "Relation between depression after stroke, antidepressant therapy, and functional recovery", J NE NE PSY, 71(2), 2001, pp. 258-261

Abstract

The aim was to evaluate the effects of poststroke depression and antidepressant therapy on the improvement of motor scores and disability, to verify if the negative effects of poststroke depression on functional recovery could be counterbalanced by taking antidepressant drugs. Results obtained before, during, and after rehabilitation-on the Barthel index, Canadian neurological scale, and Rivermead mobility index-by 49 depressed patients with stroke, who had been treated (n=25) or not treated (n=24) according to the different therapeutic approaches of their physicians, were compared with results similarly obtained by 15 non-depressed patients with stroke. Analysis was by multivariate analysis of variance for repeated measuresThere was a non-significant difference between the groups in their motor and functional scores, and a significant improvement on time. A significant interaction between group and time was seen. This interaction was particularly significant on the Rivermead mobility index, and was due to the fact that the recovery of non-treated depressed patients with stroke was less thanthe non-depressed and the depressed but treated patients with stroke. Furthermore, recovery from depression was significantly greater in treated thanin non-treated depressed patients with stroke. In conclusion, poststroke depression has negative effects on functional recovery, and a pharmacological treatment of depression can counterbalance this effect.

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Documento generato il 28/11/20 alle ore 00:20:31