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Titolo:
How does the degree of carotid stenosis affect the accuracy and interobserver variability of magnetic resonance angiography?
Autore:
Wardlaw, JM; Lewis, SC; Humphrey, P; Young, G; Collie, D; Warlow, CP;
Indirizzi:
Western Gen Hosp NHS Trust, Dept Clin Neurosci, Edinburgh EH4 2XU, Midlothian, Scotland Western Gen Hosp NHS Trust Edinburgh Midlothian Scotland EH42XU Scotland Western Gen Hosp NHS Trust, Dept Neuroradiol, Edinburgh EH4 2XU, Midlothian, Scotland Western Gen Hosp NHS Trust Edinburgh Midlothian Scotland EH4 2XU Scotland Walton Ctr Neurol, Liverpool, Merseyside, England Walton Ctr Neurol Liverpool Merseyside England pool, Merseyside, England Middlesbrough Gen Hosp, Dept Neurol, Middlesbrough, Cleveland, England Middlesbrough Gen Hosp Middlesbrough Cleveland England leveland, England
Titolo Testata:
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
fascicolo: 2, volume: 71, anno: 2001,
pagine: 155 - 160
SICI:
0022-3050(200108)71:2<155:HDTDOC>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
ARTERY STENOSIS; RISK;
Keywords:
magnetic resonance angiography; digital subtraction; carotid stenosis; endarterectomy;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
12
Recensione:
Indirizzi per estratti:
Indirizzo: Wardlaw, JM Western Gen Hosp NHS Trust, Dept Clin Neurosci, Bramwell Dott Bldg,Crewe Rd, Edinburgh EH4 2XU, Midlothian, Scotland Western Gen Hosp NHSTrust Bramwell Dott Bldg,Crewe Rd Edinburgh Midlothian Scotland EH4 2XU
Citazione:
J.M. Wardlaw et al., "How does the degree of carotid stenosis affect the accuracy and interobserver variability of magnetic resonance angiography?", J NE NE PSY, 71(2), 2001, pp. 155-160

Abstract

Objectives-The accuracy of magnetic resonance angiography (MRA) was determined in patients with recently symptomatic tight (80%-99%) carotid stenosis(on Doppler ultrasound), and the effect of stenosis severity on the accuracy and interobserver variability of MRA was studied. Methods-Forty four consecutive patients undergoing intra-arterial angiography (IAA) before carotid endarterectomy were prospectively studied, in two centres with identical MR scanners and sequences. All patients had undergone Doppler ultrasound, showing a 70% or worse carotid stenosis on the symptomatic side. MRA and IAA were done during the same admission. The MRA films were each independently and blindly read for percentage stenosis (signal gap if present) by four observers. The IA angiograms were read separately by one observer, blind to symptoms, and Doppler and MRA results. Results-Signal gaps on MRA were seen in stenoses ranging from 67% to 99% on intraarterial angiography. Magnetic resonance angiograms consistently overestimated the percentage stenosis according to intraarterial angiography. Clinically significant misclassification of stenosis occurred according to MRA in 7% of patients, and was more frequent as carotid stenosis increased. Conclusion-Significant diagnostic errors occur with MRA in patients with tight carotid stenosis. Any morbidity occurring as a result of misclassification by MRA is likely to be offset by the avoidance of complications; however, this could only be determined with certainty in a randomised controlledtrial.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/09/20 alle ore 19:58:44