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Titolo:
Quantitative volumetry in patients with carotid disease - Effects of acetazolamide
Autore:
Eicke, BM; Bahr, RR; Buss, E; Doberenz, C; Paulus, W;
Indirizzi:
Univ Mainz, Dept Neurol, D-55101 Mainz, Germany Univ Mainz Mainz GermanyD-55101 nz, Dept Neurol, D-55101 Mainz, Germany Univ Gottingen, Dept Clin Neurophysiol, D-3400 Gottingen, Germany Univ Gottingen Gottingen Germany D-3400 ysiol, D-3400 Gottingen, Germany
Titolo Testata:
JOURNAL OF NEUROIMAGING
fascicolo: 1, volume: 11, anno: 2001,
pagine: 13 - 17
SICI:
1051-2284(200101)11:1<13:QVIPWC>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
CEREBRAL BLOOD-FLOW; LAUSANNE STROKE REGISTRY; ARTERY-DISEASE; TRANSCRANIAL DOPPLER; VASOMOTOR REACTIVITY; DUPLEX SONOGRAPHY; CO2; ENDARTERECTOMY; VELOCITY; OCCLUSIONS;
Keywords:
ultrasonics; blood flow velocity; cerebrovascular; circulation; carotid artery diseases;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
26
Recensione:
Indirizzi per estratti:
Indirizzo: Eicke, BM Univ Mainz, Dept Neurol, Langenbeckstr 1, D-55101 Mainz, GermanyUniv Mainz Langenbeckstr 1 Mainz Germany D-55101 Mainz, Germany
Citazione:
B.M. Eicke et al., "Quantitative volumetry in patients with carotid disease - Effects of acetazolamide", J NEUROIMAG, 11(1), 2001, pp. 13-17

Abstract

The intracranial effects of acetazolamide on flow velocities can be monitored noninvasively by transcranial Doppler (TCD) sonography. Extracranial volume flow changes can now reliably be measured with color duplex M-mode systems. The authors tested the volumetric effects of acetazolamide in patients with high-grade unilateral carotid disease to quantify the amount of Row changes. Patients in group 1 had a high-grade > 70% internal carotid artery(ICA) stenosis, without collateral Row through the ophthalmic artery (OA). Patients with occluded ICA were included in group 2 (patent OA collateralization) or group 3 (no OA collateralization) (n = 6 per group). In group 1,common carotid artery (CCA) volume flow in the stenotic (normal contralateral) side increased from 271 (388) ml/min by 52 (54)% with 1 g aceta- zolamide intravenously. Simultaneously, middle cerebral artery (MCA) flow velocities increased from 54 (56) cm/s by 47 (53)%. In group 2, extracranial volume flow increased from 166 (444) ml/min by 19 (52)%. MCA Row velocities increased from 43 (65) cm/s by 13 (30)%. In group 3, volume flow increased from 159 (467) ml/min by 2 (46)%. Intracranial flow velocities rose from 49 (54) cm/s by 27 (41)%. Volume Row data showed the expected decline in patients with high-grade ICA stenosis and even more pronounced in patients with occlusion of the vessel. Cerebral reserve capacity was less sufficient in patients with a patent OA, despite an additional supply of 30 ml/min, indicating a hemodynamically critical situation.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 10/04/20 alle ore 01:27:22