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Titolo:
Dopamine transporter immunoreactivity in peripheral blood lymphocytes in Parkinson's disease
Autore:
Caronti, B; Antonini, G; Calderaro, C; Ruggieri, S; Palladini, G; Pontieri, FE; Colosimo, C;
Indirizzi:
Univ La Sapienza, Dept Neurosci, I-00185 Rome, Italy Univ La Sapienza Rome Italy I-00185 , Dept Neurosci, I-00185 Rome, Italy INM Neuromed, Pozzilli, IS, Italy INM Neuromed Pozzilli IS ItalyINM Neuromed, Pozzilli, IS, Italy
Titolo Testata:
JOURNAL OF NEURAL TRANSMISSION
fascicolo: 7, volume: 108, anno: 2001,
pagine: 803 - 807
SICI:
0300-9564(2001)108:7<803:DTIIPB>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
EXPRESSION; DIAGNOSIS;
Keywords:
dopamine; lymphocytes; Parkinson's disease;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
12
Recensione:
Indirizzi per estratti:
Indirizzo: Colosimo, C Univ La Sapienza, Dept Neurosci, Viale Univ 30 Box 41, I-00185Rome, Italy Univ La Sapienza Viale Univ 30 Box 41 Rome Italy I-00185 taly
Citazione:
B. Caronti et al., "Dopamine transporter immunoreactivity in peripheral blood lymphocytes in Parkinson's disease", J NEURAL TR, 108(7), 2001, pp. 803-807

Abstract

There is increasing interest in the identification of biological markers for the early diagnosis of Parkinson's disease (PD). Previous studies indicate changes of dopamine content, tyrosine hydroxylase immunoreactivity and dopamine receptors in peripheral blood lymphocytes (PBL) in PD. Here we demonstrate a reduction of dopamine transporter immunoreactivity in PBL in the early clinical stages of the disease. These findings contribute to our understanding of the peripheral dopamine system in PD.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/12/20 alle ore 19:49:38