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Titolo:
Timing of the administration of tranexamic acid for maximum reduction in blood loss in arthroplasty of the knee
Autore:
Tanaka, N; Sakahashi, H; Sato, E; Hirose, K; Ishima, T; Ishii, S;
Indirizzi:
Sapporo Med Univ, Sch Med, Dept Orthopaed Surg, Sapporo, Hokkaido, Japan Sapporo Med Univ Sapporo Hokkaido Japan d Surg, Sapporo, Hokkaido, Japan
Titolo Testata:
JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME
fascicolo: 5, volume: 83B, anno: 2001,
pagine: 702 - 705
SICI:
0301-620X(200107)83B:5<702:TOTAOT>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
THROMBOSIS; INHIBITORS; APROTININ;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
31
Recensione:
Indirizzi per estratti:
Indirizzo: Tanaka, N Sapporo Gorinbashi Orthopaed Hosp, Gorinbashi Hlth Care Facil & Hosp, Minami Ku, 2-1 Kawazoe, Sapporo, Hokkaido 0050802, Japan Sapporo Gorinbashi Orthopaed Hosp 2-1 Kawazoe Sapporo Hokkaido Japan 0050802
Citazione:
N. Tanaka et al., "Timing of the administration of tranexamic acid for maximum reduction in blood loss in arthroplasty of the knee", J BONE-BR V, 83B(5), 2001, pp. 702-705

Abstract

We studied 99 patients who were undergoing total knee arthroplasty (TKA) to determine the optimum protocol for the administration of tranexamic acid (TNA) in order to reduce blood loss. It decreased by more than 40% after the administration of TNA, The haemostatic effect was greatest when TNA was given preoperatively and on deflation of the tourniquet, There was no increase in the incidence of adverse affects in the patients receiving TNA, compared with a control group. We conclude that two injections of TNA, one given preoperatively and one on deflation of the tourniquet, significantly reduce blood loss without increasing the risk of thromboembolic complications.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 06:02:12