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Titolo:
Exercise training-induced triglyceride lowering negatively correlates withDHEA levels in men with type 2 diabetes
Autore:
Boudou, P; de Kerviler, E; Erlich, D; Vexiau, P; Gautier, JF;
Indirizzi:
St Louis Univ Hosp, Dept Hormonal Biol, F-75475 Paris 10, France St Louis Univ Hosp Paris France 10 rmonal Biol, F-75475 Paris 10, France St Louis Univ Hosp, Dept Radiol, F-75475 Paris, France St Louis Univ HospParis France F-75475 pt Radiol, F-75475 Paris, France St Louis Univ Hosp, Dept Biochem B, F-75475 Paris 10, France St Louis UnivHosp Paris France 10 t Biochem B, F-75475 Paris 10, France St Louis Univ Hosp, Dept Diabetol, F-75475 Paris 10, France St Louis Univ Hosp Paris France 10 pt Diabetol, F-75475 Paris 10, France
Titolo Testata:
INTERNATIONAL JOURNAL OF OBESITY
fascicolo: 8, volume: 25, anno: 2001,
pagine: 1108 - 1112
SICI:
0307-0565(200108)25:8<1108:ETTLNC>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
IMPAIRED GLUCOSE-TOLERANCE; DEHYDROEPIANDROSTERONE-SULFATE; CARDIOVASCULAR MORTALITY; INSULIN SENSITIVITY; HEART-DISEASE; RISK-FACTORS; BODY-FAT; MELLITUS; NIDDM; TESTOSTERONE;
Keywords:
type 2 diabetes; exercise training; triglycerides; DHEA; body composition;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
37
Recensione:
Indirizzi per estratti:
Indirizzo: Boudou, P St Louis Univ Hosp, Dept Hormonal Biol, 1 Ave Claude Vellefaux, F-75475 Paris 10, France St Louis Univ Hosp 1 Ave Claude Vellefaux Paris France 10 rance
Citazione:
P. Boudou et al., "Exercise training-induced triglyceride lowering negatively correlates withDHEA levels in men with type 2 diabetes", INT J OBES, 25(8), 2001, pp. 1108-1112

Abstract

OBJECTIVE: To investigate the effect of an exercise training program on lipid profile in correlation with DHEA level and body weight and body composition in type 2 diabetic men. DESIGN: Longitudinal, controlled clinical intervention study with exercisetraining consisting of an 8 week supervised program of aerobic exercise (75% VO2 peak, 45 min), twice a week and intermittent exercise, once a week, on a bicyle ergometer. SUBJECTS: Sixteen men (age 45.4 +/- 7.2 y (mean +/- s.d.), HbA1c 8.15 +/- 1.7%, body mass index (BMI) 29.6 +/- 4.6 kg/m(2)) were randomly divided into two groups: trained group (n = 8) and control group (n = 8). MEASUREMENTS: Lipid, apo- and lipoprotein and DHEA concentrations. Cross-sectional areas of subcutaneous and visceral adipose tissue and mid-thigh muscle by magnetic resonance imaging. RESULTS: Training decreased visceral (153.25 +/- 38.55 vs 84.20 +/- 21.30cm(2), P < 0.001), subcutaneous (241.55 +/- 49.55 vs 198.00 +/- 39.99 cm(2) P < 0.001) adipose tissue area and triglyceride levels (2.59 +/- 1.90 vs 1.79 +/- 1.08 nmol/l, P < 0.05) and increased mid-thigh muscle cross-sectional area (148.30 +/- 36.10 vs 184.35 +/- 35.85 cm(2), P < 0.001), and DHEA Levels (11.00 +/- 3.10 vs 14.25 +/- 4.10 nmol/l, P < 0.05) with no modification in body weight. Changes in triglycerides were negatively correlated withchanges in DHEA (r= -0.81, P=0.03). This correlation was independent of changes in abdominal fat distribution. CONCLUSION: Training decreases abdominal fat depots, improves muscular mass and affects favourably triglyceride and DHEA levels. Changes in triglycerides and DHEA were inversely related.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/01/20 alle ore 07:33:37