Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Screening women at high risk of breast cancer on the basis of evidence
Autore:
Warren, R;
Indirizzi:
Addenbrookes Hosp, Dept Radiol, Cambridge CB2 2QQ, England Addenbrookes Hosp Cambridge England CB2 2QQ , Cambridge CB2 2QQ, England
Titolo Testata:
EUROPEAN JOURNAL OF RADIOLOGY
fascicolo: 1, volume: 39, anno: 2001,
pagine: 50 - 59
SICI:
0720-048X(200107)39:1<50:SWAHRO>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
HORMONE REPLACEMENT THERAPY; COST-EFFECTIVENESS ANALYSIS; ATOMIC-BOMB SURVIVORS; FAMILY HISTORY; OVARIAN-CANCER; ATAXIA-TELANGIECTASIA; IONIZING-RADIATION; INHERITED BREAST; YOUNGER WOMEN; FOLLOW-UP;
Keywords:
breast cancer; family history; screening; BRCA gene mutation; mammography; radiation risk;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
136
Recensione:
Indirizzi per estratti:
Indirizzo: Warren, R Addenbrookes Hosp, Dept Radiol, Hills Rd, Cambridge CB2 2QQ, England Addenbrookes Hosp Hills Rd Cambridge England CB2 2QQ Q, England
Citazione:
R. Warren, "Screening women at high risk of breast cancer on the basis of evidence", EUR J RAD, 39(1), 2001, pp. 50-59

Abstract

Geneticists are able to identify the risk of breast cancer. Strategies on offer include prevention, early diagnosis by screening, and prophylactic surgery. This paper analyses the evidence for offering screening. The radiation dose of mammography has been measured, but the risk is not fully known. Mammography screening of women of 40-50 years in the normal population has known effect. Little evidence is available for women under 40 years or for women with genetic susceptibility to breast cancer. Dense parenchymal pattern is associated with high grade cancers, and is both a risk factor and a reason for impaired screening sensitivity. Whether this applies to younger women or women at high risk is speculative. The pathological features of thecancers in gene carriers show differences from those occurring in normal women. This work should be correlated with imaging features. There is no literature to support the use of newer imaging methods in these women. Ultrasound and MRI avoid radiation and may be useful in dense breasts. SestaMIBI and PET scanning are not yet mature enough for screening, and may never havesuch a role. Any newer modality must be subjected to a formal randomised trial before being offered to screen women at highrisk. (C) 1001 Elsevier Science Ireland Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/01/21 alle ore 04:01:46