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Titolo:
Effect of chronic morphine administration on glucose tolerance and insulinbinding to isolated rat adipocytes
Autore:
Sood, A; Thakur, VS; Karmarkar, MG; Ahuja, MMS;
Indirizzi:
So Illinois Univ, Sch Med, Dept Internal Med, Div Endocrinol Metab & Mol Med, Springfield, IL 62794 USA So Illinois Univ Springfield IL USA 62794 Med, Springfield, IL 62794 USA All India Inst Med Sci, Dept Endocrinol & Metab, New Delhi 110029, India All India Inst Med Sci New Delhi India 110029 b, New Delhi 110029, India All India Inst Med Sci, De Addict Ctr, New Delhi 110029, India All India Inst Med Sci New Delhi India 110029 r, New Delhi 110029, India
Titolo Testata:
ENDOCRINE RESEARCH
fascicolo: 1-2, volume: 27, anno: 2001,
pagine: 215 - 221
SICI:
0743-5800(2001)27:1-2<215:EOCMAO>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
BETA-ENDORPHIN; GLUCAGON; METABOLISM; ADDICTION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Sood, A So Illinois Univ, Sch Med, Dept Internal Med, Div Endocrinol Metab& Mol Med, 701 N 1st St,Suite D405B,POB 19636, Springfield, IL 62794 USA So Illinois Univ 701 N 1st St,Suite D405B,POB 19636 Springfield IL USA 62794
Citazione:
A. Sood et al., "Effect of chronic morphine administration on glucose tolerance and insulinbinding to isolated rat adipocytes", ENDOCRINE R, 27(1-2), 2001, pp. 215-221

Abstract

Morphine addiction was induced in six male Wistar rats. Improved glucose tolerance (peak value less by 28%, p < 0.01) was observed in chronically morphinized rats as compared to the control rats, injected with saline. An increase in the maximal specific binding of I-125-labeled insulin to unit membrane area of adipocytes was observed in the experimental group (p < 0.01). The changes in insulin receptor number could be responsible for the improved glucose tolerance observed during morphine addiction.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 13:21:23