Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Chronic depression in the elderly - Approaches for prevention
Autore:
Reynolds, CF; Alexopoulos, GS; Katz, IR; Lebowitz, BD;
Indirizzi:
Univ Pittsburgh, Sch Med, Dept Psychiat, Western Psychiat Inst & Clin, Pittsburgh, PA 15213 USA Univ Pittsburgh Pittsburgh PA USA 15213 & Clin, Pittsburgh, PA 15213 USA Cornell Univ, Coll Med, White Plains, NY 10605 USA Cornell Univ White Plains NY USA 10605 ll Med, White Plains, NY 10605 USA Univ Penn, Sch Med, Philadelphia, PA 19104 USA Univ Penn Philadelphia PA USA 19104 , Sch Med, Philadelphia, PA 19104 USA NIMH, Bethesda, MD 20892 USA NIMH Bethesda MD USA 20892NIMH, Bethesda, MD 20892 USA
Titolo Testata:
DRUGS & AGING
fascicolo: 7, volume: 18, anno: 2001,
pagine: 507 - 514
SICI:
1170-229X(2001)18:7<507:CDITE->2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
RECURRENT MAJOR DEPRESSION; RANDOMIZED CONTROLLED TRIAL; GERIATRIC DEPRESSION; LATE-LIFE; INTERPERSONAL PSYCHOTHERAPY; NORTRIPTYLINE; OUTCOMES; RECOVERY; TERM; DISCONTINUATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
43
Recensione:
Indirizzi per estratti:
Indirizzo: Reynolds, CF Univ Pittsburgh, Sch Med, Dept Psychiat, Western Psychiat Inst & Clin, Room 1135E,3811 OHara St, Pittsburgh, PA 15213 USA Univ Pittsburgh Room 1135E,3811 OHara St Pittsburgh PA USA 15213
Citazione:
C.F. Reynolds et al., "Chronic depression in the elderly - Approaches for prevention", DRUG AGING, 18(7), 2001, pp. 507-514

Abstract

Depression in old age frequently follows a chronic and/or relapsing course, related to medical comorbidity, cognitive impairment and depletion of psychosocial resources. As endorsed by the US National Institutes of Health (NIH) Consensus Development Conference on the Diagnosis and Treatment of LateLife Depression, a major goal of treatment is to prevent relapse, recurrence and chronicity. We believe that most, if not all, elderly patients with major depressive episodes are appropriate candidates for maintenance therapy, because of the vulnerability to relapse and recurrence and because of the favourable benefit to risk ratio of available treatments. Antidepressant pharmacotherapy isthe mainstay of this therapeutic goal, but psychosocial approaches (especially interpersonal psychotherapy) have also been shown to contribute significantly to prevention of a chronic depressive illness and to prevention of the disability that attends depression. Studies published to date have established the long term or maintenance efficacy of the tricyclic antidepressant nortriptyline. Current, ongoing studies are addressing the maintenance efficacy of paroxetine and citalopram toprolong recovery in depression associated with old age. These studies are focusing particularly on patients aged 70 years and above, who are at high risk of recurrence, and on patients in primary care settings, where under-recognition and under-treatment of depression in the elderly have been costly from a public health perspective in terms of increased medical utilisation, burden to patients and families, and high rates of suicide. Depression in old age is a major contributor to the global burden of illness-related disability, but it is extremely treatable if appropriate pharmacotherapy is prescribed and accepted by patients and their caregivers.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/20 alle ore 07:36:19