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Titolo:
Prevalence of peptic lesions in asymptomatic, healthy volunteers
Autore:
Ecclissato, C; Carvalho, AFN; Ferraz, JGP; de Nucci, G; De Souza, CAF; Pedrazzoli, J;
Indirizzi:
Univ Sao Francisco, Sch Med, Clin Pharmacol & Gastroenterol Unit, Dept Pathol, BR-12900000 Braganca Paulista, SP, Brazil Univ Sao Francisco BragancaPaulista SP Brazil BR-12900000 BC, SP, Brazil UNICAMP, Fac Med Sci, Dept Internal Med, Discipline Gastroenterol & Gastroctr, Campinas, SP, Brazil UNICAMP Campinas SP Brazil stroenterol & Gastroctr, Campinas, SP, Brazil Univ Sao Paulo, Inst Biomed Sci, Dept Pharmacol, Cartesius Analyt Unit, Sao Paulo, Brazil Univ Sao Paulo Sao Paulo Brazil artesius Analyt Unit, Sao Paulo, Brazil
Titolo Testata:
DIGESTIVE AND LIVER DISEASE
fascicolo: 5, volume: 33, anno: 2001,
pagine: 403 - 406
SICI:
1590-8658(200106/07)33:5<403:POPLIA>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
HELICOBACTER-PYLORI INFECTION; POINT PREVALENCE; ULCER; GASTRITIS; DISEASE; METRONIDAZOLE; INDIVIDUALS; OMEPRAZOLE; ABSORPTION; ENDOSCOPY;
Keywords:
asymptomatic volunteers; dyspepsia; Helicobacter pylori; ulcer;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Pedrazzoli, J Univ Sao Francisco, Sch Med, Clin Pharmacol & Gastroenterol Unit, Dept Pathol, Av Sao Francisco de Assis 218, BR-12900000 Braganca Paulista, SP, Brazil Univ Sao Francisco Av Sao Francisco de Assis 218 Braganca Paulista SP Brazil BR-12900000 BC
Citazione:
C. Ecclissato et al., "Prevalence of peptic lesions in asymptomatic, healthy volunteers", DIG LIVER D, 33(5), 2001, pp. 403-406

Abstract

Aim. To investigate the presence of lesions of the upper gastrointestinal tract of asymptomatic, healthy volunteers undergoing clinical pharmacology studies. Material and Methods. A series of 53 volunteers (45 male, 23 Helicobacter pylori negative and 30 Helicobacter pylori positive) underwent upper gastrointestinal endoscopy. Helicobacter pylori status was assessed using two methods (rapid urease test and histology) from antral and corpus biopsies. Results. Peptic lesions were found in 24 (45%) subjects: erosive oesophagitis, gastric/duodenal ulcers and gastric/duodenal erosions were found in 23%, 9% and 36% of these volunteers, respectively. Helicobacter pylori-positive subjects had significantly (p<0.05) more gastroduodenal lesions than Helicobacter pylori negative individuals (12/30 vs 3/23). The presence of peptic ulcers and erosive oesophagitis was similar Helicobacter pylori-positiveand -negative individuals. Conclusions. The possibility that peptic lesions might exist in otherwise asymptomatic, healthy individuals cannot be ruled out. Helicobacter pylori-positive individuals have a significantly higher incidence of gastric and duodenal lesions than Helicobacter pylori negative subjects.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/04/20 alle ore 22:09:03