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Titolo:
AUTOMATIC SEMANTIC PRIMING OF NOUNS AND VERBS IN PATIENTS WITH ALZHEIMERS-DISEASE
Autore:
BUSHELL CM; MARTIN A;
Indirizzi:
NIMH,LAB BRAIN & COGNIT,BLDG 10,RM4C-104,10 CTR DR,MSC 1366 BETHESDA MD 20896 NIMH,LAB BRAIN & COGNIT BETHESDA MD 20896
Titolo Testata:
Neuropsychologia
fascicolo: 8, volume: 35, anno: 1997,
pagine: 1059 - 1067
SICI:
0028-3932(1997)35:8<1059:ASPONA>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
LEXICAL-DECISION TASK; SENILE DEMENTIA; SPREADING ACTIVATION; NEURAL SYSTEMS; HUMAN BRAIN; MEMORY; KNOWLEDGE; IMPAIRMENT; RETRIEVAL; DEFICITS;
Keywords:
SEMANTIC MEMORY; APHASIA; CATEGORY-SPECIFIC DEFICITS; LANGUAGE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
67
Recensione:
Indirizzi per estratti:
Citazione:
C.M. Bushell e A. Martin, "AUTOMATIC SEMANTIC PRIMING OF NOUNS AND VERBS IN PATIENTS WITH ALZHEIMERS-DISEASE", Neuropsychologia, 35(8), 1997, pp. 1059-1067

Abstract

The status of semantic representations of nouns (concrete and abstract) and verbs (motion and non-motion) was investigated in patients withAlzheimer's disease (AD). Nouns and verbs have been argued to activate different neural substrates, given the selective difficulties reported for one or the other grammatical class in patients with focal lesions. Additionally, category-specific deficits have been reported for either abstract or concrete words, often in patients with bilateral neuropathology. We looked for these types of dissociations in patients with AD in a semantic priming experiment using a pronunciation task and ashort stimulus onset asynchrony. The normal control subjects demonstrated automatic activation for both concrete nouns and motion verbs. The AD patients, however, demonstrated priming effects for concrete nouns, but not for motion verbs. This dissociation between concrete nouns and motion verbs found for the AD patients is discussed in terms of differences in the nature of semantic representations involving multiplephysical and functional attributes in the case of concrete nouns, butonly motion attributes in the case of motion verbs. Moreover, the typical distribution of neuropathology associated with AD may put motion verbs at risk, particularly given the neuroanatomical considerations suggested by recent positron emission tomography (PET) studies.

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Documento generato il 28/03/20 alle ore 22:31:05