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Titolo:
Myocardial imaging with I-123-metaiodobenzylguanidine in essential hypertension and renovascular hypertension
Autore:
Ohya, Y; Sasaki, M; Fujishima, S; Kagiyama, S; Onaka, U; Kaseda, S; Ohmori, S; Kuwabara, Y; Abe, I; Fujishima, M;
Indirizzi:
Kyushu Univ, Fac Med, Dept Internal Med 2, Higashi Ku, Fukuoka 8128582, Japan Kyushu Univ Fukuoka Japan 8128582 2, Higashi Ku, Fukuoka 8128582, Japan Kyushu Univ, Fac Med, Dept Radiol, Higashi Ku, Fukuoka 8128582, Japan Kyushu Univ Fukuoka Japan 8128582 ol, Higashi Ku, Fukuoka 8128582, Japan
Titolo Testata:
CLINICAL AND EXPERIMENTAL HYPERTENSION
fascicolo: 4, volume: 23, anno: 2001,
pagine: 293 - 304
SICI:
1064-1963(200105)23:4<293:MIWIIE>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
SYMPATHETIC NERVOUS-SYSTEM; LEFT-VENTRICULAR MASS; I-123 METAIODOBENZYLGUANIDINE; HYPERTROPHIC CARDIOMYOPATHY; HEART; IODINE-123-MIBG; INNERVATION; ANGIOTENSIN; WASHOUT; FAILURE;
Keywords:
metaiodobenzylguanidine; left ventricular hypertrophy; renovascular hypertension; essential hypertension; scintigraphy; renin; angiotensin II;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
34
Recensione:
Indirizzi per estratti:
Indirizzo: Ohya, Y Kyushu Univ, Fac Med, Dept Internal Med 2, Higashi Ku, Maidashi 3-1-1, Fukuoka 8128582, Japan Kyushu Univ Maidashi 3-1-1 Fukuoka Japan 8128582 a 8128582, Japan
Citazione:
Y. Ohya et al., "Myocardial imaging with I-123-metaiodobenzylguanidine in essential hypertension and renovascular hypertension", CLIN EXP HY, 23(4), 2001, pp. 293-304

Abstract

Iodine-123 metaiodobenzylguanidine (MIBG) myocardial imaging is consideredto reflect cardiac sympathetic function. We performed myocardial MIBG scintigraphy and echocardiography in 27 patients with essential hypertension (EHT), 7 patients with renovascular hypertension (RVHT). and 8 normotensive subjects (NT) to investigate alterations in MIBG myocardial imaging in the presence of hypertension and left ventricular hypertrophy (LVH). EHT were divided into two groups based on LV wall thickness: EHT with LVH group (greater than or equal to 13 mm, n=15) and EHT without LVH group (< 13 mm, n=12). The delayed uptake of MIBG was decreased, and the washout rate of MIBG wasgreater in the EHT with LVH group than EHT without LVH group or NT group. The washout rate was correlated with LV mass and LV diastolic function (as assessed by mitral flow). In RVHT group, the MIBG washout rate increased even without LVH, compared with NT and EHT without LVH groups. In summary, the washout rate of MIBG increased in parallel with the development of LVH inEHT and increased independently of the LV mass in RVHT. Cardiac sympathetic function could be altered in hypertensive LVH and in renovascular hypertension.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/12/20 alle ore 01:10:46