Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Engineered cartilage, bone, joints, and menisci - Potential for temporomandibular joint reconstruction
Autore:
Glowacki, J;
Indirizzi:
Harvard Univ, Sch Med, Brigham & Womens Hosp, Boston, MA 02115 USA HarvardUniv Boston MA USA 02115 gham & Womens Hosp, Boston, MA 02115 USA Harvard Univ, Sch Dent Med, Skeletal Biol Res Ctr, Massachusetts Gen Hosp,Boston, MA 02115 USA Harvard Univ Boston MA USA 02115 sachusetts Gen Hosp,Boston, MA 02115 USA
Titolo Testata:
CELLS TISSUES ORGANS
fascicolo: 3, volume: 169, anno: 2001,
pagine: 302 - 308
SICI:
1422-6405(2001)169:3<302:ECBJAM>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUMAN INTERVERTEBRAL DISC; 3-DIMENSIONAL CULTURE; ARTICULAR-CARTILAGE; DEMINERALIZED BONE; EXPERIMENTAL-MODEL; IN-VITRO; CHONDROCYTES; REGENERATION; REPLACEMENT; FIBROBLASTS;
Keywords:
tissue engineering; temporomandibular joint; meniscus; cartilage; bone;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
41
Recensione:
Indirizzi per estratti:
Indirizzo: Glowacki, J Harvard Univ, Sch Med, Brigham & Womens Hosp, 75 Francis St, Boston, MA 02115 USA Harvard Univ 75 Francis St Boston MA USA 02115 n, MA 02115 USA
Citazione:
J. Glowacki, "Engineered cartilage, bone, joints, and menisci - Potential for temporomandibular joint reconstruction", CELLS T ORG, 169(3), 2001, pp. 302-308

Abstract

Reconstruction of many musculoskeletal structures can be accomplished by bone grafting and implantation of prostheses. Alternate approaches are needed, however, for repair of complex structures such as articular cartilage surfaces and the temporomandibular meniscus and joint. Tissue engineering, either cell-free or cell-based, offers promise because of recent advances in materials research and in our knowledge of the cellular and molecular mechanisms of tissue repair. There are th ree considerations in designing a construct for engineered tissue: the source of cells, if any; the nature of thecarrier or scaffold; and use, if any, of genes, factors, or adjuvants. Autogenous cells, often expanded in vitro, have been useful for cartilage tissue engineering. Precursor/progenitor cells are advantageous for bone tissue. There are many natural and synthetic resorbable materials with good biocompatibility and tissue compatibility that can be modified to have the porosity and mechanical properties needed for specific applications. The scaffolds can also be modified to provide biological signals to augment repair andintegration. Copyright (C) 2001 S. Karger AG, Basel.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/04/20 alle ore 06:48:59