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Titolo:
Bone loss - Therapeutic approaches for preventing bone loss in inflammatory arthritis
Autore:
Rehman, Q; Lane, NE;
Indirizzi:
Univ Calif San Francisco, San Francisco, CA 94110 USA Univ Calif San Francisco San Francisco CA USA 94110 ancisco, CA 94110 USA
Titolo Testata:
ARTHRITIS RESEARCH
fascicolo: 4, volume: 3, anno: 2001,
pagine: 221 - 227
SICI:
1465-9913(2001)3:4<221:BL-TAF>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
TUMOR-NECROSIS-FACTOR; OSTEOCLAST-LIKE CELLS; INTERLEUKIN-1 RECEPTOR ANTAGONIST; COLONY-STIMULATING FACTOR; GAMMA-INDUCING FACTOR; TNF FAMILY MEMBER; RHEUMATOID-ARTHRITIS; MESSENGER-RNA; FACTOR-ALPHA; OSTEOPROTEGERIN LIGAND;
Keywords:
osteoclast; osteoprotegerin; receptor activator of nuclear factor-kappa B ligand; rheumatoid arthritis;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
81
Recensione:
Indirizzi per estratti:
Indirizzo: Lane, NE Univ Calif San Francisco, Room 3300,Bldg 30,1001 Potrero Ave, SanFrancisco, CA 94110 USA Univ Calif San Francisco Room 3300,Bldg 30,1001 Potrero Ave San Francisco CA USA 94110
Citazione:
Q. Rehman e N.E. Lane, "Bone loss - Therapeutic approaches for preventing bone loss in inflammatory arthritis", ARTHRITIS R, 3(4), 2001, pp. 221-227

Abstract

Inflammatory arthritides are commonly characterized by localized and generalized bone loss. Localized bone loss in the form of joint erosions and periarticular osteopenia is a hallmark of rheumatoid arthritis, the prototype of inflammatory arthritis. Recent studies have highlighted the importance of receptor activator of nuclear factor-kappaB ligand (RANKL)-dependent osteoclast activation by inflammatory cells and subsequent bone loss. In this article, we review the pathogenesis of inflammatory bone loss and explore the possible therapeutic interventions to prevent it.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 09:27:59