Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
The consideration of immunotherapy in the treatment of allergic asthma
Autore:
Creticos, PS;
Indirizzi:
Johns Hopkins Univ, Sch Med, Dept Med, Div Clin Immunol & Allergy, Baltimore, MD 21205 USA Johns Hopkins Univ Baltimore MD USA 21205 llergy, Baltimore, MD 21205 USA
Titolo Testata:
ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY
fascicolo: 1, volume: 87, anno: 2001, supplemento:, 1
pagine: 13 - 27
SICI:
1081-1206(200107)87:1<13:TCOIIT>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
GRASS-POLLEN IMMUNOTHERAPY; HISTAMINE-RELEASING-FACTOR; DERMATOPHAGOIDES-PTERONYSSINUS EXTRACT; DUST MITE ALLERGENS; CAT-INDUCED ASTHMA; DOUBLE-BLIND TRIAL; RAGWEED HAY-FEVER; NASAL CHALLENGE; HOUSE DUST; INFLAMMATORY MEDIATORS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
76
Recensione:
Indirizzi per estratti:
Indirizzo: Creticos, PS Johns Hopkins Asthma & Allergy Ctr, 5501 Hopkins Bayview Circle,Room 2B-57, Baltimore, MD 21224 USA Johns Hopkins Asthma & Allergy Ctr 5501 Hopkins Bayview Circle,Room 2B-57 Baltimore MD USA 21224
Citazione:
P.S. Creticos, "The consideration of immunotherapy in the treatment of allergic asthma", ANN ALLER A, 87(1), 2001, pp. 13-27

Abstract

Background: Immunotherapy (IT) has undergone rigorous trials to evaluate its therapeutic benefit in the treatment of allergic respiratory disease. The tools of molecular biology have provided a framework with which to begin to understand the mechanistic effects of IT on the underlying inflammatory component of allergic respiratory disease. Results: The clinical relevance of these observations belies our understanding of allergic inflammation as the subsoil for the development of abnormal airway physiology, heightened bronchial reactivity, and the development of chronic asthmatic symptomatology. Conclusions: IT provides the potential to downregulate this inflammatory cascade, reduce IgE antibody production, and attenuate symptoms. Conceptually, early intervention of allergic disease holds the most promise as a therapeutic intervention capable of arresting the progression of the disease, altering the severity of the disease, and/or preventing the development of the respiratory disease process.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/10/20 alle ore 08:33:24