Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Gender differences in cocaine craving among non-treatment-seeking individuals with cocaine dependence
Autore:
Elman, I; Karlsgodt, KH; Gastfriend, DR;
Indirizzi:
Massachusetts Gen Hosp, Dept Psychiat, Addict Serv, Boston, MA 02114 USA Massachusetts Gen Hosp Boston MA USA 02114 ict Serv, Boston, MA 02114 USA Harvard Univ, Sch Med, Boston, MA 02114 USA Harvard Univ Boston MA USA 02114 vard Univ, Sch Med, Boston, MA 02114 USA
Titolo Testata:
AMERICAN JOURNAL OF DRUG AND ALCOHOL ABUSE
fascicolo: 2, volume: 27, anno: 2001,
pagine: 193 - 202
SICI:
0095-2990(2001)27:2<193:GDICCA>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
SEX-DIFFERENCES; NUCLEUS-ACCUMBENS; ABUSERS; DEPRESSION; HYPERSENSITIVITY; PSYCHOPATHOLOGY; EXPERIENCES; VOLUNTEERS; DISORDERS; ADDICTION;
Keywords:
depression; dopamine; estrogen; HRSD; POMS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Citazioni:
36
Recensione:
Indirizzi per estratti:
Indirizzo: Elman, I Massachusetts Gen Hosp, Dept Psychiat, Addict Serv, 15 Parkman St,WACC-812, Boston, MA 02114 USA Massachusetts Gen Hosp 15 Parkman St,WACC-812 Boston MA USA 02114
Citazione:
I. Elman et al., "Gender differences in cocaine craving among non-treatment-seeking individuals with cocaine dependence", AM J DRUG A, 27(2), 2001, pp. 193-202

Abstract

The purpose of this pilot study was to evaluate potential gender differences in cocaine craving among non-treatment seekers with cocaine dependence. We examined 10 female and Il male individuals matched by demographic characteristics and severity of drug use; we used a multidimensional questionnaire that assesses various aspects of craving: (a) current intensity, (b) projected intensity, (c) resistance to use cocaine, (d) responsiveness to drug-related conditioned stimuli, and (e) imagined likelihood of use if in a setting with access to drugs. Other instruments utilized were the Hamilton Rating Scale for Depression and Addiction Severity Index. Female subjects had hight I total craving scores (p < .05), with post hoc tests showing more present desire to use cocaine and responsivity to drug-conditioned stimuli, along with lower scores on the desire not to use cocaine. In exploratory analyses, we found greater depressive symptomatology (p = .02) and severity offamily/social problems (p = .02) in ti males than their males counterparts. These results suggest that gender may influence different aspects of cocaine craving. As estrogen is purported to modulate craving-related dopaminergic systems, further studies will be needed to confirm these observed gender differences and to investigate their possible mechanisms, particularly estrogen-dopamine interactions and their effect on craving and mood.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/09/20 alle ore 09:37:47