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Titolo:
Role of vessel size as a predictor for the occurrence of in-stent restenosis in patients with diabetes mellitus
Autore:
Suselbeck, T; Latsch, A; Siri, H; Gonska, B; Poerner, T; Pfleger, S; Schumacher, B; Borggrefe, M; Haase, KK;
Indirizzi:
Univ Heidelberg, Klinikum Mannheim, Med Klin 1, Dept Cardiol, D-68167 Mannheim, Germany Univ Heidelberg Mannheim Germany D-68167 diol, D-68167 Mannheim, Germany
Titolo Testata:
AMERICAN JOURNAL OF CARDIOLOGY
fascicolo: 3, volume: 88, anno: 2001,
pagine: 243 - 247
SICI:
0002-9149(20010801)88:3<243:ROVSAA>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY-ARTERY DISEASE; BALLOON ANGIOPLASTY; PLACEMENT; IMPLANTATION; TERM; EXPERIENCE; 4-YEAR;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Haase, KK Univ Heidelberg, Klinikum Mannheim, Med Klin 1, Dept Cardiol, Theodor Ufer1-3, D-68167 Mannheim, Germany Univ Heidelberg Theodor Ufer 1-3 Mannheim Germany D-68167 rmany
Citazione:
T. Suselbeck et al., "Role of vessel size as a predictor for the occurrence of in-stent restenosis in patients with diabetes mellitus", AM J CARD, 88(3), 2001, pp. 243-247

Abstract

Intracoronary stents have been shown to reduce the rate of restenosis whencompared with balloon angioplasty, but in-stent restenosis continues to bean important clinical problem. It was therefore the aim of this registry to identify procedural and angiographic predictors for the occurrence of in-stent restenosis. We analyzed 368 patients with 421 lesions who underwent coronary stent implantation between January 1998 and February 2000. Indications for the placement of a coronary stent were severe dissections (37%), suboptimal angiographic results (38%), restenotic lesions (20%), and graft lesions (4%). Angiographic follow-up was obtained in 270 patients (73%) with 293 lesions after 6 months. Clinical and angiographic variables were analyzed by univariate and multivariate models for the ability to predict the occurrence of in-stent restenosis, defined as a diameter stenosis > 50%. In-stent restenosis was angiographically documented in 67 patients and 68 lesions (23%). Under all tested variables the reference luminal diameter before stent implantation (p = 0.006) and diabetes mellitus (p = 0.023) were identified as independent predictors for the occurrence of in-stent restenosis. The comparison of diabetic and nondiabetic patients according to vessel sizerevealed a 2 times higher rate of in-stent restenosis in small vessels (44% vs 23%, p = 0.002), whereas in vessels >3.0 mm the rate of in-stent restenosis was not significantly different between the 2 groups. In this registry, the clinical variable diabetes and the procedural variable reference vessel size were independent predictors for the occurrence of in-stent restenosis. In these patients, the rate of in-stent restenosis was as high as 45%. (C) 2001 by Excerpta Medica, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/07/20 alle ore 22:31:03