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Titolo:
Primary aldosteronism: Are we diagnosing and operating on too few patients?
Autore:
Gordon, RD; Stowasser, M; Rutherford, JC;
Indirizzi:
Univ Queensland, Greenslopes Hosp, Dept Med, Endocrine Hypertens Res Unit,Brisbane, Qld 4120, Australia Univ Queensland Brisbane Qld Australia 4120 Brisbane, Qld 4120, Australia
Titolo Testata:
WORLD JOURNAL OF SURGERY
fascicolo: 7, volume: 25, anno: 2001,
pagine: 941 - 947
SICI:
0364-2313(200107)25:7<941:PAAWDA>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
HYPERALDOSTERONISM TYPE-I; LAPAROSCOPIC ADRENALECTOMY; HYPERTENSION; ADENOMA; LATERALIZATION; GENE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
37
Recensione:
Indirizzi per estratti:
Indirizzo: Gordon, RD Univ Queensland, Greenslopes Hosp, Dept Med, Endocrine Hypertens Res Unit,Brisbane, Qld 4120, Australia Univ Queensland Brisbane Qld Australia 4120 ld 4120, Australia
Citazione:
R.D. Gordon et al., "Primary aldosteronism: Are we diagnosing and operating on too few patients?", WORLD J SUR, 25(7), 2001, pp. 941-947

Abstract

Many cases of potentially curable primary aldosteronism are currently likely to be diagnosed as essential hypertension unless screening tests based on suppression of renin are tarried out in all hypertensive patients. More than half of the patients with primary aldosteronism detected in this way have normal circulating potassium levels, so measurement of potassium is not enough to exclude primary aldosteronism. When primary aldosteronism is diagnosed, fewer than one-third of patients are suitable for surgery as initialtreatment, but this still represents a significant percentage of hypertensive patients. After excluding glucocorticoid-suppressible primary aldosteronism, adrenal venous sampling is essential to detect unilateral production of aldosterone and diagnose angiotensin-responsive aldosterone-producing adenoma. One cannot rely on the computed tomography scan. If all hypertensivepatients are screened for primary aldosteronism and the workup is continued methodically in those with a positive screening test, patients with unilateral overproduction of aldosterone who potentially can be cured surgicallyare not denied the possibility of cure.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/04/20 alle ore 10:49:53