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Titolo:
Parasite adhesion and immune evasion in placental malaria
Autore:
Beeson, JG; Reeder, JC; Rogerson, SJ; Brown, GV;
Indirizzi:
Univ Melbourne, Royal Melbourne Hosp, Dept Med, Parkville, Vic 3050, Australia Univ Melbourne Parkville Vic Australia 3050 arkville, Vic 3050, Australia
Titolo Testata:
TRENDS IN PARASITOLOGY
fascicolo: 7, volume: 17, anno: 2001,
pagine: 331 - 337
SICI:
1471-4922(200107)17:7<331:PAAIEI>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
FALCIPARUM-INFECTED ERYTHROCYTES; CHONDROITIN-SULFATE-A; MICROVASCULAR ENDOTHELIAL-CELLS; RED-BLOOD-CELLS; PLASMODIUM-FALCIPARUM; PREGNANT-WOMEN; CYTOADHERENCE CHARACTERISTICS; MEMBRANE PROTEIN-1; ADHERENCE RECEPTOR; HYALURONIC-ACID;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
65
Recensione:
Indirizzi per estratti:
Indirizzo: Beeson, JG Univ Melbourne, Royal Melbourne Hosp, Dept Med, Parkville, Vic 3050, Australia Univ Melbourne Parkville Vic Australia 3050 ic 3050, Australia
Citazione:
J.G. Beeson et al., "Parasite adhesion and immune evasion in placental malaria", TRENDS PARA, 17(7), 2001, pp. 331-337

Abstract

Parasite sequestration in the placenta is a key feature of infection by Plasmodium falciparum during pregnancy and is associated with severe adverse outcomes for both mother and baby. Here, James Beeson and colleagues draw together the findings of recent studies on parasite mechanisms that mediate this process. They review evidence for novel parasite va ria nts that appear able to evade pre-existing immunity, for the adhesion of Fl falciparum-infected erythrocytes to placental glycosaminoglycans land the molecular basis of these parasite properties) and for the expression of var genes encoding the variant antigen and adhesive ligand P. falciparum-erythrocyte membrane protein 1 (PfEMP1).

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 10:34:15