Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Regulation of T-cell apoptosis in inflammatory bowel disease: to die or not to die, that is the mucosal question
Autore:
Neurath, MF; Finotto, S; Fuss, I; Boirivant, M; Galle, PR; Strober, W;
Indirizzi:
Univ Mainz, Med Clin 1, Immunol Lab, D-55131 Mainz, Germany Univ Mainz Mainz Germany D-55131 1, Immunol Lab, D-55131 Mainz, Germany NIH, Mucosal Immun Sect, Bethesda, MD 20814 USA NIH Bethesda MD USA 20814NIH, Mucosal Immun Sect, Bethesda, MD 20814 USA La Sapienza, Dept Immunol, I-35461 Rome, Italy La Sapienza Rome Italy I-35461 pienza, Dept Immunol, I-35461 Rome, Italy
Titolo Testata:
TRENDS IN IMMUNOLOGY
fascicolo: 1, volume: 22, anno: 2001,
pagine: 21 - 26
SICI:
1471-4906(200101)22:1<21:ROTAII>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
FAS-MEDIATED APOPTOSIS; TUMOR-NECROSIS-FACTOR; CROHNS-DISEASE; EXPERIMENTAL COLITIS; LYMPHOCYTE APOPTOSIS; ANTIBODY CA2; CD2 PATHWAY; IFN-GAMMA; MICE; RESISTANCE;
Tipo documento:
Editorial Material
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
38
Recensione:
Indirizzi per estratti:
Indirizzo: Neurath, MF Univ Mainz, Med Clin 1, Immunol Lab, D-55131 Mainz, Germany Univ Mainz Mainz Germany D-55131 Lab, D-55131 Mainz, Germany
Citazione:
M.F. Neurath et al., "Regulation of T-cell apoptosis in inflammatory bowel disease: to die or not to die, that is the mucosal question", TRENDS IMMU, 22(1), 2001, pp. 21-26

Abstract

T-cell resistance against apoptosis contributes to inappropriate T-cell accumulation and the perpetuation of chronic mucosal inflammation in inflammatory bowel diseases (IBDs). Anti-interleukin-12 (IL-12) and anti-IL-6 receptor antibodies suppress colitis activity by the induction of T-cell apoptosis. These findings have important implications for the design of effective treatment regimens in IBD.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/04/20 alle ore 01:51:21