Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Evolution of bone marrow transplantation - the original immunotherapy
Autore:
Campbell, JDM; Cook, G; Holyoake, TL;
Indirizzi:
Royal Infirm, Dept Med, Acad Transfus Med Unit, Glasgow G31 2ER, Lanark, Scotland Royal Infirm Glasgow Lanark Scotland G31 2ER ow G31 2ER, Lanark, Scotland
Titolo Testata:
TRENDS IN IMMUNOLOGY
fascicolo: 2, volume: 22, anno: 2001,
pagine: 88 - 92
SICI:
1471-4906(200102)22:2<88:EOBMT->2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
CHRONIC MYELOID-LEUKEMIA; CHRONIC MYELOGENOUS LEUKEMIA; TYROSINE KINASE INHIBITOR; CYTOTOXIC T-LYMPHOCYTES; MINOR HISTOCOMPATIBILITY ANTIGENS; STEM-CELL TRANSPLANTATION; ABL-POSITIVE CELLS; CLASS-I MOLECULES; BCR-ABL; PHILADELPHIA-CHROMOSOME;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
38
Recensione:
Indirizzi per estratti:
Indirizzo: Holyoake, TL Royal Infirm, Dept Med, Acad Transfus Med Unit, 10 Alexandra Parade, Glasgow G31 2ER, Lanark, Scotland Royal Infirm 10 Alexandra Parade Glasgow Lanark Scotland G31 2ER
Citazione:
J.D.M. Campbell et al., "Evolution of bone marrow transplantation - the original immunotherapy", TRENDS IMMU, 22(2), 2001, pp. 88-92

Abstract

Allogeneic bone-marrow transplantation (BMT) has provided a curative treatment option for chronic myeloid leukaemia (CML) over the past 20-30 years. New drugs - signal transduction inhibitors - that target the bcr-abl oncogene have the potential to render such transplantation procedures obsolete and provide hope for those without a suitable donor (approximate to 60% of patients). Here, we discuss how new drug and immune-based approaches could becombined to enhance treatment of this already 'curable' malignancy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/05/20 alle ore 15:04:48