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Titolo:
Fibroblasts regulate the switch from acute resolving to chronic persistentinflammation
Autore:
Buckley, CD; Pilling, D; Lord, JM; Akbar, AN; Scheel-Toellner, D; Salmon, M;
Indirizzi:
Univ Birmingham, Div Immun & Infect, MRC, Ctr Immune Regulat, Birmingham B15 2TT, W Midlands, England Univ Birmingham Birmingham W Midlands England B15 2TT W Midlands, England Royal Free & Univ Coll Med Sch, Dept Clin Immunol, London NW3 2QG, EnglandRoyal Free & Univ Coll Med Sch London England NW3 2QG n NW3 2QG, England
Titolo Testata:
TRENDS IN IMMUNOLOGY
fascicolo: 4, volume: 22, anno: 2001,
pagine: 199 - 204
SICI:
1471-4906(200104)22:4<199:FRTSFA>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
T-CELLS; RHEUMATOID-ARTHRITIS; LYMPHOID NEOGENESIS; LUNG FIBROBLASTS; CUTTING EDGE; EXPRESSION; CHEMOKINES; APOPTOSIS; MEMORY; CYTOKINES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
46
Recensione:
Indirizzi per estratti:
Indirizzo: Buckley, CD Univ Birmingham, Div Immun & Infect, MRC, Ctr Immune Regulat, Birmingham B15 2TT, W Midlands, England Univ Birmingham Birmingham W Midlands England B15 2TT England
Citazione:
C.D. Buckley et al., "Fibroblasts regulate the switch from acute resolving to chronic persistentinflammation", TRENDS IMMU, 22(4), 2001, pp. 199-204

Abstract

Fibroblasts are important sentinel cells in the immune system and, here, it is proposed that these cells play a critical role in the switch from acute inflammation to adaptive immunity and tissue repair. It is suggested thatchronic inflammation occurs because of disordered fibroblast behaviour in which failure to switch off their inflammatory programme leads to the inappropriate survival and retention of leukocytes within inflamed tissue.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 06:31:26