Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
The role of MHC class II-restricted tumor antigens and CD4(+) T cells in antitumor immunity
Autore:
Wang, RF;
Indirizzi:
Baylor Coll Med, Ctr Cell & Gene Therapy, Houston, TX 77030 USA Baylor Coll Med Houston TX USA 77030 Gene Therapy, Houston, TX 77030 USA Baylor Coll Med, Dept Immunol, Houston, TX 77030 USA Baylor Coll Med Houston TX USA 77030 Dept Immunol, Houston, TX 77030 USA
Titolo Testata:
TRENDS IN IMMUNOLOGY
fascicolo: 5, volume: 22, anno: 2001,
pagine: 269 - 276
SICI:
1471-4906(200105)22:5<269:TROMCI>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
HLA-DR MOLECULES; HUMAN-MELANOMA; INFILTRATING LYMPHOCYTES; METASTATIC MELANOMA; CANCER-IMMUNOTHERAPY; AUTOIMMUNE VITILIGO; TRANSGENIC MICE; DENDRITIC CELLS; IFN-GAMMA; IN-VIVO;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
77
Recensione:
Indirizzi per estratti:
Indirizzo: Wang, RF Baylor Coll Med, Ctr Cell & Gene Therapy, 1 Baylor Plaza, Houston, TX 77030 USA Baylor Coll Med 1 Baylor Plaza Houston TX USA 77030 TX 77030 USA
Citazione:
R.F. Wang, "The role of MHC class II-restricted tumor antigens and CD4(+) T cells in antitumor immunity", TRENDS IMMU, 22(5), 2001, pp. 269-276

Abstract

The identification of tumor antigens has generated a resurgence of interest in immunotherapy for cancer. However, both clinical and animal studies suggest that therapeutic strategies that have mainly focused on the use of CD8(+) T cells (and MHC class I-restricted tumor antigens) are not effective in eliminating cancer cells. Recent interest has been directed towards the use of CD4(+) T cells in generating antitumor immunity. To this end, the identification of MHC class It-restricted tumor antigens that can stimulate CD4(+) T cells might provide opportunities for developing effective cancer vaccines.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/04/20 alle ore 13:29:55