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Titolo:
The amplification of TCR signaling by dynamic membrane microdomains
Autore:
Viola, A;
Indirizzi:
Univ Padua, Dept Biomed Sci, I-35121 Padua, Italy Univ Padua Padua ItalyI-35121 ua, Dept Biomed Sci, I-35121 Padua, Italy
Titolo Testata:
TRENDS IN IMMUNOLOGY
fascicolo: 6, volume: 22, anno: 2001,
pagine: 322 - 327
SICI:
1471-4906(200106)22:6<322:TAOTSB>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
T-CELL ACTIVATION; GPI-ANCHORED PROTEINS; LIPID RAFTS; TYROSINE KINASE; SRC-FAMILY; CYTOSKELETAL REORGANIZATION; THYMOCYTE DEVELOPMENT; DEFICIENT MICE; RECEPTOR; CD28;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
61
Recensione:
Indirizzi per estratti:
Indirizzo: Viola, A Univ Padua, Dept Biomed Sci, Via G Colombo 3, I-35121 Padua, Italy Univ Padua Via G Colombo 3 Padua Italy I-35121 5121 Padua, Italy
Citazione:
A. Viola, "The amplification of TCR signaling by dynamic membrane microdomains", TRENDS IMMU, 22(6), 2001, pp. 322-327

Abstract

Modulation of T-cell receptor (TCR) signaling is essential for the regulation of T-cell responses to infectious agents. Recently, many laboratories have suggested that TCR triggering might be compartmentalized in plasma membrane microdomains called rafts. Results on the role of lipid rafts as signaling units in TCR triggering suggest that rafts might be used by T cells tofine-tune their immune responsiveness.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/04/20 alle ore 05:12:45