Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
In vivo assessment of the effects of estrogen on human brain
Autore:
van Amelsvoort, T; Compton, J; Murphy, D;
Indirizzi:
Inst Psychiat, Dept Psychol Med, London SE5 8AF, England Inst Psychiat London England SE5 8AF sychol Med, London SE5 8AF, England
Titolo Testata:
TRENDS IN ENDOCRINOLOGY AND METABOLISM
fascicolo: 6, volume: 12, anno: 2001,
pagine: 273 - 276
SICI:
1043-2760(200108)12:6<273:IVAOTE>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSITRON-EMISSION TOMOGRAPHY; CEREBRAL BLOOD-FLOW; GROWTH-HORMONE RESPONSE; REPLACEMENT THERAPY; MENSTRUAL-CYCLE; POSTMENOPAUSAL WOMEN; ALZHEIMERS-DISEASE; OLDER WOMEN; PUERPERAL PSYCHOSIS; COGNITIVE FUNCTION;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
57
Recensione:
Indirizzi per estratti:
Indirizzo: van Amelsvoort, T Inst Psychiat, Dept Psychol Med, De Crespigny Pk, LondonSE5 8AF, England Inst Psychiat De Crespigny Pk London England SE5 8AF nd
Citazione:
T. van Amelsvoort et al., "In vivo assessment of the effects of estrogen on human brain", TRENDS ENDO, 12(6), 2001, pp. 273-276

Abstract

There is increasing evidence from animal and in vitro studies to suggest that estrogen might have neuroprotective effects, and several plausible physiological mechanisms have been proposed. However, it is not yet fully understood how estrogen affects the human brain. There are several techniques that are currently employed for in vivo assessment of brain structure and function in humans, including neuropsychological and neuroendocrine testing, computerized tomography, structural and functional magnetic resonance imaging, magnetic resonance spectroscopy, single photon emission spectroscopy andpositron emission tomography. Results from studies investigating the effects of estrogen on the female brain using the above techniques are reviewed here. The current data from humans suggest that the use of estrogen hormone-replacement therapy (HRT) in healthy, postmenopausal women might reduce the risk of developing Alzheimer's disease (AD) and preserve certain aspects of cognitive function, The use of HRT in postmenopausal women might also modulate neurotransmitter function end can increase cerebral blood flow in a regionally specific and task-dependent manner. In addition, the neuroprotective effects of HRT might depend on the length of its use. However, there is very little evidence at present that HRT is an effective treatment for established AD.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/07/20 alle ore 08:55:13