Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Hemangioma-like lesions in chronic liver disease: Diagnostic evaluation inpatients
Autore:
Caturelli, E; Pompili, M; Bartolucci, F; Siena, DA; Sperandeo, M; Andriulli, A; Bisceglia, M;
Indirizzi:
Osped Casa Sollievo Sofferenza, Ist Ricovero & Cura Carattere Sci, Div Gastroenterol, Div Med,Dept Anat & Histopathol, I-71013 San Giovanni Rotondo, Foggia, Italy Osped Casa Sollievo Sofferenza San Giovanni Rotondo Foggia Italy I-71013 Univ Cattolica Sacro Cuore, Dept Internal Med, Rome, Italy Univ Cattolica Sacro Cuore Rome Italy e, Dept Internal Med, Rome, Italy Univ Ancona, Dept Radiol & Diagnost Imaging, I-60128 Ancona, Italy Univ Ancona Ancona Italy I-60128 Diagnost Imaging, I-60128 Ancona, Italy
Titolo Testata:
RADIOLOGY
fascicolo: 2, volume: 220, anno: 2001,
pagine: 337 - 342
SICI:
0033-8419(200108)220:2<337:HLICLD>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
FINE-NEEDLE BIOPSY; HEPATIC CAVERNOUS HEMANGIOMAS; DYNAMIC BOLUS CT; HEPATOCELLULAR-CARCINOMA; COMPUTED-TOMOGRAPHY; ULTRASOUND; ULTRASONOGRAPHY; US; TIME; SIGN;
Keywords:
angioma; liver, CT; liver, SPECT; liver, US; liver neoplasms;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
39
Recensione:
Indirizzi per estratti:
Indirizzo: Caturelli, E Osped Casa Sollievo Sofferenza, Ist Ricovero & Cura CarattereSci, Div Gastroenterol, Div Med,Dept Anat & Histopathol, Viale Cappuccini,I-71013 San Giovanni Rotondo, Foggia, Italy Osped Casa Sollievo SofferenzaViale Cappuccini San Giovanni Rotondo Foggia Italy I-71013
Citazione:
E. Caturelli et al., "Hemangioma-like lesions in chronic liver disease: Diagnostic evaluation inpatients", RADIOLOGY, 220(2), 2001, pp. 337-342

Abstract

PURPOSE: To quantify the risk of misdiagnosis of focal hepatic lesions manifesting at ultrasonography (US) as typical hemangiomas in a population at high risk for hepatocellular carcinoma (HCC) and to identify the most effective approach to their diagnostic evaluation. MATERIALS AND METHODS: A total of 1,982 patients with newly diagnosed cirrhosis underwent US and serum ol-fetoprotein determinations for early detection of HCC. Focal lesions with typical features of hemangioma were evaluated with confirmatory findings of contrast material-enhanced dynamic or spiral computed tomography (CT) and/or single photon emission CT with technetium99m-labeled red blood cells and, in the absence of confirmatory imaging findings, US-guided fine-needle biopsy. Patients whose initial US scan depicted no lesions or hemangiomas were enrolled in a US follow-up program. All hemangioma-like lesions detected during follow-up were evaluated, or biopsy was performed. RESULTS: US depicted hemangioma-like lesions in 44 of 1,982 patients: 22 hemangiomas and 22 HCCs. Hemangioma-like lesions detected during follow-up in 1,648 patients were HCCs (n = 22) or dysplastic nodules (n = 4). Only 85 (22%) of 383 patients with HCC had cl-fetoprotein levels suggestive of the diagnosis. The probability of a diagnosis of HCC (or preneoplastic lesion) is 100% for hemangioma-like lesions depicted on subsequent US scans. CONCLUSION: If initial US examination of a cirrhotic liver depicts a hemangioma, confirmatory findings of imaging studies are necessary since 50% of hemangiomas in this study were hyperechogenic HCCs. US-guided biopsy can besafely performed, and its findings can be used to confirm the diagnosis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 15:37:54