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Titolo:
Issues in pediatric asthma
Autore:
Helms, PJ;
Indirizzi:
Univ Aberdeen, Dept Child Hlth, Aberdeen AB25 2ZD, Scotland Univ AberdeenAberdeen Scotland AB25 2ZD th, Aberdeen AB25 2ZD, Scotland
Titolo Testata:
PEDIATRIC PULMONOLOGY
, , anno: 2001, supplemento:, 21
pagine: 49 - 56
SICI:
8755-6863(2001):<49:IIPA>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
CHILDHOOD ASTHMA; INHALED CORTICOSTEROIDS; LUNG-FUNCTION; PRESCHOOL-CHILDREN; PULMONARY-FUNCTION; CHRONIC-BRONCHITIS; WHEEZY BRONCHITIS; DIAGNOSED ASTHMA; NATURAL-HISTORY; YOUNG-ADULTS;
Keywords:
asthma; wheezing syndromes; viral-associated wheeze; atopy; inhaled corticosteroids; asthma guidelines; children;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
52
Recensione:
Indirizzi per estratti:
Indirizzo: Helms, PJ Univ Aberdeen, Dept Child Hlth, Aberdeen AB25 2ZD, Scotland UnivAberdeen Aberdeen Scotland AB25 2ZD en AB25 2ZD, Scotland
Citazione:
P.J. Helms, "Issues in pediatric asthma", PEDIAT PULM, 2001, pp. 49-56

Abstract

Different wheezing syndromes can carry the diagnostic label of "asthma," especially in very young children, and an accurate differential diagnosis isessential for improving outcomes, Because presenting symptoms are similar,making a rapid, accurate differential diagnosis is often daunting. Asthma can, eventually, be distinguished from other wheezing disorders based on differences in symptomatology, pathophysiology, and disease evolution. Once diagnosed, inhaled corticosteroids (ICS) remain the cornerstone of treatmentin persistent pediatric asthma. Compelling evidence supports the benefits of these agents in reducing asthma-related morbidity and mortality and in preventing airway remodeling. As a result, ICS use in young children with asthma has grown substantially in recent years. Questions are being raised about the appropriateness of early and long-term use of ICS in young children, and whether ICS are overused in this population. Because of the challenges faced by clinicians in differentiating asthma from the other childhood wheezing disorders often present in young children, it may be best to delay the use of regular ICS therapy until a definitive diagnosis can be established. Alternatives to ICS (such as the leukotriene receptor antagonists) should also be considered to avoid the growth-suppressing potential of steroidsin the management of mild asthma. (C) 2001 Wiley-Liss. Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/03/20 alle ore 23:09:22