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Titolo:
Pediatric asthma: "Real world" measures of effectiveness
Autore:
Fink, RJ;
Indirizzi:
George Washington Univ, Childrens Natl Med Ctr, Sch Hlth Sci, Dept AllergyImmunol & Pulm Med, Washington, DC 20010 USA George Washington Univ Washington DC USA 20010 , Washington, DC 20010 USA
Titolo Testata:
PEDIATRIC PULMONOLOGY
, , anno: 2001, supplemento:, 21
pagine: 31 - 37
SICI:
8755-6863(2001):<31:PA"WMO>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
TRIAL;
Keywords:
asthma; efficacy; effectiveness; compliance; adherence; measures; children;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
8
Recensione:
Indirizzi per estratti:
Indirizzo: Fink, RJ George Washington Univ, Childrens Natl Med Ctr, Sch Hlth Sci, Dept AllergyImmunol & Pulm Med, 111 Michigan Ave NW, Washington, DC 20010 USA George Washington Univ 111 Michigan Ave NW Washington DC USA 20010
Citazione:
R.J. Fink, "Pediatric asthma: "Real world" measures of effectiveness", PEDIAT PULM, 2001, pp. 31-37

Abstract

In the treatment of pediatric asthma, measuring the effectiveness of an intervention in terms of cost or therapeutic value can be a challenging process. Parameters that should be considered in determining the cost effectiveness of an intervention vary considerably. In clinical therapeutic trials ofpediatric asthma, subtle patient selection biases, difficulties in choosing and assessing treatment outcomes in young children, and the highly variable nature of asthma symptomatology can compromise valid measurements of thetherapeutic effectiveness of an intervention. Ideally. outcome measurements in asthma should reflect "real world" conditions. They should be as broad-based as possible and include both objective measures of pulmonary function and subjective measures of quality-of-life evaluated over the long term. Patient adherence is thus a critical variable that influences the ultimate effectiveness of treatment. The rate of patient adherence is influenced notonly by drug characteristics such as route of administration and dosing frequency, but also by the impact of treatment on a patient's quality of life. Because asthma is a chronic disease with variable symptomatology, clinical trials investigating the cost and therapeutic effectiveness of asthma interventions must evaluate real-world variables in long-term trials. This article will provide information regarding proper assessment of an intervention's cost and therapeutic value. (C) 2001 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 16:07:17