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Titolo:
Invasion of epithelial cells by Trichinella spiralis: In vitro observations
Autore:
Romaris, F; Appleton, JA;
Indirizzi:
Cornell Univ, Coll Vet Med, James A Baker Inst Anim Hlth, Ithaca, NY 14853USA Cornell Univ Ithaca NY USA 14853 aker Inst Anim Hlth, Ithaca, NY 14853USA
Titolo Testata:
PARASITE-JOURNAL DE LA SOCIETE FRANCAISE DE PARASITOLOGIE
fascicolo: 2, volume: 8, anno: 2001, supplemento:, S
pagine: S48 - S50
SICI:
1252-607X(200106)8:2<S48:IOECBT>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
PARASITIC NEMATODE; RAPID EXPULSION; SUCKLING RATS; ANTIBODIES; LARVAE; GLYCOPROTEIN; EXPRESSION; CLONING; ANTIGEN;
Keywords:
Trichinella spiralis; invasion; epithelial cells; in vitro;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Appleton, JA Cornell Univ, Coll Vet Med, James A Baker Inst Anim Hlth, Ithaca, NY 14853USA Cornell Univ Ithaca NY USA 14853 m Hlth, Ithaca, NY 14853USA
Citazione:
F. Romaris e J.A. Appleton, "Invasion of epithelial cells by Trichinella spiralis: In vitro observations", PARASITE, 8(2), 2001, pp. S48-S50

Abstract

It has been known for many years that Trichinella spiralis initiates infection by penetrating the columnar epithelium of the small intestine, however, the mechanisms used by the parasite in the establishment of its intramulticellular niche in the intestine ate unknown. The recent demonstration thatinvasion also occurs in vitro when infective larvae of T. spiralis are inoculated onto cultures of epithelial cells provides a model that allows the direct observation of the process by which the parasite recognizes, invadesand migrates within the epithelium. The finding that penetration of the cell membrane or induction of plasma membrane wounds by larvae do not always result in invasion argue in favor of some kind of host-parasite communication in successful invasion. In this sense, the in vitro model of invasion provides a readily manipulated and controlled system to investigate both parasite, and host cell requirements for invasion.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/09/20 alle ore 22:43:42