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Titolo:
Decreased carotid artery distensibility as a sign of early atherosclerosisin viscose rayon workers
Autore:
Kotseva, K; Braeckman, L; Duprez, D; De Bacquer, D; De Buyzere, M; Van De Veire, N; Vanhoorne, M;
Indirizzi:
Univ Hosp Sv Ivan Rilski, Natl Ctr Occupat Dis, Sofia 1431, Bulgaria Univ Hosp Sv Ivan Rilski Sofia Bulgaria 1431 t Dis, Sofia 1431, Bulgaria State Univ Ghent Hosp, Dept Publ Hlth, B-9000 Ghent, Belgium State Univ Ghent Hosp Ghent Belgium B-9000 l Hlth, B-9000 Ghent, Belgium State Univ Ghent Hosp, Dept Cardiol & Angiol, B-9000 Ghent, Belgium State Univ Ghent Hosp Ghent Belgium B-9000 Angiol, B-9000 Ghent, Belgium
Titolo Testata:
OCCUPATIONAL MEDICINE-OXFORD
fascicolo: 4, volume: 51, anno: 2001,
pagine: 223 - 229
SICI:
0962-7480(200106)51:4<223:DCADAA>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
DENSITY-LIPOPROTEIN CHOLESTEROL; ISCHEMIC-HEART-DISEASE; CARBON-DISULFIDE; CARDIOVASCULAR MORTALITY; BLOOD-PRESSURE; HYPERTENSION; INDUSTRY; EXPOSURE; ARTERIOSCLEROSIS; STIFFNESS;
Keywords:
arterial compliance; arterial distensibility; blood pressure; carbon disulphide; common carotid artery; heart rate; lipid metabolism; occupational exposure;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
37
Recensione:
Indirizzi per estratti:
Indirizzo: Kotseva, K Univ Hosp Sv Ivan Rilski, Natl Ctr Occupat Dis, 15 Dimitar Nestorov Str, Sofia 1431, Bulgaria Univ Hosp Sv Ivan Rilski 15 Dimitar NestorovStr Sofia Bulgaria 1431
Citazione:
K. Kotseva et al., "Decreased carotid artery distensibility as a sign of early atherosclerosisin viscose rayon workers", OCCUP MED-O, 51(4), 2001, pp. 223-229

Abstract

Carbon disulphide (CS2) is known to accelerate atherosclerosis and to increase the risk for cardiovascular diseases. To assess the effect of CS2 on the functional (distensibility and compliance) and the structural (intima media thickness) properties of the common carotid artery, and blood pressure and lipid metabolism parameters, a cross-sectional study on 85 workers froma viscose rayon factory and 37 controls was carried out. Exposure to CS2 was assessed by personal monitoring and was well below the threshold limit value-time weighted average. Carotid arterial wall properties were determined using a non-invasive ultrasound wall movement detector system. No significant effect of CS2 on blood pressure, total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol or triglycerides was found. Among the vascular parameters studied, only distensibility was significantly lower and heart rate was significantly higher in exposed subjects compared with the controls. In conclusion, occupational exposure to CS2 may cause early alterations in arterial elastic properties in young individuals, and even before lipid and clinical findings have occurred, important functional changes in the vessel wall are present.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/01/20 alle ore 09:33:48