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Titolo:
A facile synthesis of 5 '-end solid-anchored, 3 '-end free oligodeoxyribonucleotides via the (5 '-> 3 ')-elongated phosphoramidite strategy
Autore:
Sakakura, A; Hayakawa, Y;
Indirizzi:
Nagoya Univ, Grad Sch Human Informat, Lab Bioorgan Chem, Nagoya, Aichi 4648601, Japan Nagoya Univ Nagoya Aichi Japan 4648601 Chem, Nagoya, Aichi 4648601, Japan
Titolo Testata:
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
fascicolo: 3, volume: 20, anno: 2001,
pagine: 213 - 227
SICI:
1525-7770(2001)20:3<213:AFSO5'>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
OLIGONUCLEOTIDE-PEPTIDE HYBRIDS; PHASE SYNTHESIS; NUCLEOTIDE SYNTHESIS; DERIVATIVES; DNA; PROTECTION; PORPHYRINS; ATTACHMENT; SUPPORTS; CLEAVAGE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Hayakawa, Y Nagoya Univ, Grad Sch Human Informat, Lab Bioorgan Chem, Nagoya, Aichi 4648601, Japan Nagoya Univ Nagoya Aichi Japan 4648601 , Aichi 4648601, Japan
Citazione:
A. Sakakura e Y. Hayakawa, "A facile synthesis of 5 '-end solid-anchored, 3 '-end free oligodeoxyribonucleotides via the (5 '-> 3 ')-elongated phosphoramidite strategy", NUCLEOS NUC, 20(3), 2001, pp. 213-227

Abstract

It is demonstrated that not only N-2- but also O-6-protection of the guanine base is necessary for obtaining the oligodeoxyribonucleotides in high yields and at a high purity in the solid-phase synthesis via the (5 ' --> 3 ')-chain elongated phosphoramidite approach.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 23:33:16