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Titolo:
Long-term follow-up of patients diagnosed with alcohol dependence or alcohol abuse who were evaluated for liver transplantation
Autore:
Gish, RG; Lee, A; Brooks, L; Leung, J; Lau, JYN; Moore, DH;
Indirizzi:
Calif Pacific Med Ctr, Dept Med & Transplantat, San Francisco, CA 94115 USA Calif Pacific Med Ctr San Francisco CA USA 94115 Francisco, CA 94115 USA Calif Pacific Med Ctr, Dept Psychiat, San Francisco, CA 94115 USA Calif Pacific Med Ctr San Francisco CA USA 94115 Francisco, CA 94115 USA Geraldine Brush Canc Res Inst, San Francisco, CA USA Geraldine Brush Canc Res Inst San Francisco CA USA San Francisco, CA USA Univ Florida, Div Gastroenterol & Hepatol, Gainesville, FL USA Univ Florida Gainesville FL USA roenterol & Hepatol, Gainesville, FL USA
Titolo Testata:
LIVER TRANSPLANTATION
fascicolo: 7, volume: 7, anno: 2001,
pagine: 581 - 587
SICI:
1527-6465(200107)7:7<581:LFOPDW>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
HEPATITIS-C VIRUS; B VIRUS; DISEASE; CIRRHOSIS; INFECTION; SURVIVAL; RESPONSIBILITY; CONSUMPTION; RECIDIVISM; PREVALENCE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
52
Recensione:
Indirizzi per estratti:
Indirizzo: Gish, RG Calif Pacific Med Ctr, Dept Med & Transplantat, 2340 Clay St,Rm 223, San Francisco, CA 94115 USA Calif Pacific Med Ctr 2340 Clay St,Rm 223 San Francisco CA USA 94115
Citazione:
R.G. Gish et al., "Long-term follow-up of patients diagnosed with alcohol dependence or alcohol abuse who were evaluated for liver transplantation", LIVER TRANS, 7(7), 2001, pp. 581-587

Abstract

The selection of patients with cirrhosis and the diagnosis of alcohol dependence or abuse who have a long-term high probability of abstinence after orthotopic liver transplantation (OLT) may enhance patient survival and outcomes. The aim of this study is to identify factors that would predict whichpatients would consume alcohol after OLT, Sixty-one patients with a history of alcohol dependence or abuse underwent OLT from June 1989 to June 1994 and were followed up monthly for a median of 6.9 years after OLT (range, 2.5 to 9.3 years), Survival analysis techniques (Cox proportional hazard model) were used to identify patients at high risk for recidivism. Recidivism occurred in 12 of 61 patients (20%) after OLT during follow-up. Noncompliance, with a relative hazard of 20.9 (95% confidence interval [CI], 5.6 to 78.3; P < .001), and personality disorder, with a relative hazard of 6.0 (95% CI, 1.9 to 18.7; P = .002), independently predicted recidivism among patients who underwent OLT. These data indicate that specific behaviors and psychiatric diagnoses can be used to select patients at high risk for drinking alcohol before and after OLT.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/02/20 alle ore 11:58:40