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Titolo:
Effect of Shiga toxin and Shiga-like toxins on eukaryotic cells
Autore:
OLoughlin, EV; Robins-Browne, RM;
Indirizzi:
Royal Alexandra Hosp Children, Dept Gastroenterol, Westmead, NSW 2124, Australia Royal Alexandra Hosp Children Westmead NSW Australia 2124 2124, Australia Royal Childrens Hosp, Murdoch Childrens Res Inst, Parkville, Vic 3052, Australia Royal Childrens Hosp Parkville Vic Australia 3052 le, Vic 3052, Australia Univ Melbourne, Dept Microbiol & Immunol, Parkville, Vic 3052, Australia Univ Melbourne Parkville Vic Australia 3052 arkville, Vic 3052, Australia
Titolo Testata:
MICROBES AND INFECTION
fascicolo: 6, volume: 3, anno: 2001,
pagine: 493 - 507
SICI:
1286-4579(200105)3:6<493:EOSTAS>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
HEMOLYTIC-UREMIC SYNDROME; ESCHERICHIA-COLI O157-H7; VASCULAR ENDOTHELIAL-CELLS; NECROSIS-FACTOR-ALPHA; SHIGELLA-DYSENTERIAE 1; PROXIMAL TUBULE CELLS; RETROGRADE TRANSPORT; HEMORRHAGIC COLITIS; IN-VITRO; ENDOPLASMIC-RETICULUM;
Keywords:
Shiga toxin; pathogenesis; haemolytic uremic syndrome;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
152
Recensione:
Indirizzi per estratti:
Indirizzo: O'Loughlin, EV Royal Alexandra Hosp Children, Dept Gastroenterol, POB 3515, Westmead, NSW2124, Australia Royal Alexandra Hosp Children POB 3515 Westmead NSW Australia 2124
Citazione:
E.V. O'Loughlin e R.M. Robins-Browne, "Effect of Shiga toxin and Shiga-like toxins on eukaryotic cells", MICROBES IN, 3(6), 2001, pp. 493-507

Abstract

Shigella dysenteriae and Shiga-toxin-producing Escherichia call (STEC) elaborate the AB holotoxins, Shiga or Shiga-like toxins (Stx). Stx play a major role in the pathogenesis of haemorrhagic colitis and haemolytic uremic syndrome. This review provides an overview of the mechanisms of action of Stxand a model of the pathogenesis of Stx-induced disease. (C) 2001 Editions scientifiques et medicales Elsevier SAS.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/01/20 alle ore 07:06:57