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Titolo:
THE STATIC PRESSURE-VOLUME RELATIONSHIP OF THE RESPIRATORY SYSTEM DETERMINED WITH A COMPUTER-CONTROLLED VENTILATOR
Autore:
SVANTESSON C; DREFELDT B; JONSON B;
Indirizzi:
UNIV LUND HOSP,DEPT CLIN PHYSIOL S-22185 LUND SWEDEN
Titolo Testata:
Clinical physiology
fascicolo: 4, volume: 17, anno: 1997,
pagine: 419 - 430
SICI:
0144-5979(1997)17:4<419:TSPROT>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
MECHANICAL VENTILATION; DISTRESS SYNDROME; TIDAL VOLUME; CURVES; FLOW;
Keywords:
COMPLIANCE; HUMAN; LUNG; MECHANICAL VENTILATION; POSITIVE END-EXPIRATORY PRESSURE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
14
Recensione:
Indirizzi per estratti:
Citazione:
C. Svantesson et al., "THE STATIC PRESSURE-VOLUME RELATIONSHIP OF THE RESPIRATORY SYSTEM DETERMINED WITH A COMPUTER-CONTROLLED VENTILATOR", Clinical physiology, 17(4), 1997, pp. 419-430

Abstract

The pressure-volume relationship of the respiratory system offers a guideline for setting of ventilators. The occlusion method for determination of the static elastic pressure-volume (Pel(st)/V) relationship is used as a reference and the aim of the study was to improve it with respect to time consumption and precision of recording and analysis, The inspiratory Pel(st)/V curve was determined with a computer-controlled ventilator using its pressure and flow sensors. During an automatedprocedure, an operator-defined volume history preceded each of a number of study breaths. These were interrupted at different volumes evenly distributed over a predefined volume interval. Total positive end-expiratory pressure (PEEP) was measured and could be separated into its components, external PEEP and auto-PEEP. The volume relationship between the curve and the current tidal volume was defined. An analytical method for definition of a linear segment of the Pel(st)/V curve and determination of its compliance is presented. In eight healthy human anaesthetized subjects duplicate Pel(st)/V curves were studied with respect to compliance and the position along the volume axis of the linear segment. The difference in compliance between measurements was 1.6+/-1.3 ml cmH(2)O(-1) or 1.2+/-0.9%. The position of the curve differed between measurements by 15+/-10 ml or by 1.1+/-0.9%. In a patient with acute lung injury the feasibility of applying a numerical method for a more detailed description of the Pel(st)/V curve was illustrated.

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Documento generato il 30/11/20 alle ore 16:27:29