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Titolo:
Myocardial perfusion and angiographic correlations in patients with ST-segment elevation during dobutamine stress perfusion imaging
Autore:
Lee, JR; He, ZX; Dakik, H; Verani, MS;
Indirizzi:
Baylor Coll Med, Cardiol Sect, Houston, TX 77030 USA Baylor Coll Med Houston TX USA 77030 Cardiol Sect, Houston, TX 77030 USA
Titolo Testata:
JOURNAL OF NUCLEAR CARDIOLOGY
fascicolo: 3, volume: 8, anno: 2001,
pagine: 365 - 370
SICI:
1071-3581(200105/06)8:3<365:MPAACI>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
SEATTLE-HEART-WATCH; CLINICAL-SIGNIFICANCE; EXERCISE; INFARCTION; VIABILITY; TOMOGRAPHY; DISEASE;
Keywords:
dobutamine single photon emission computed tomography; ST-segment elevation; myocardial ischemia; myocardial infarction;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Verani, MS Methodist Hosp, Baylor Coll Med, 6535 Fannin,SM677, Houston, TX77030 USA Methodist Hosp 6535 Fannin,SM677 Houston TX USA 77030 77030 USA
Citazione:
J.R. Lee et al., "Myocardial perfusion and angiographic correlations in patients with ST-segment elevation during dobutamine stress perfusion imaging", J NUCL CARD, 8(3), 2001, pp. 365-370

Abstract

Background There is scanty information on the angiographic and myocardial perfusion correlates of dobutamine-induced ST-segment elevation. Methods and Results. We studied 39 patients who exhibited ST-segment elevation during dobutamine perfusion tomography and had recent coronary angiography performed tie, within 3 months of the dobutamine study). Baseline characteristics, extent of coronary artery disease, relationship of Q waves to ST-segment elevation, ischemic burden, and angiographic findings were assessed. Twenty-nine patients (74%) had prior myocardial infarction, and 77% had abnormal Q waves at baseline. Ninety-three percent of patients had abnormal perfusion imaging, Eighty percent of patients had multivessel coronary artery disease. The left ventricular ejection fraction by contrast ventriculography was 35% +/- 7% (mean +/- SD), the perfusion defect size was 32% +/-15%, and 73% of patients had some degree of myocardial ischemia, A predominance of ischemia (> 50% reversibility) occurred in 38% of patients with Q waves and in 70% of those without Q waves. There was also good agreement between the site of ST-segment elevation and the site of ischemia by perfusion imaging (79%) and between the site of ST-segment elevation and the location of the vessel with significant coronary stenosis (95 %),Conclusions. Patients with dobutamine-induced ST-segment elevation have a depressed left ventricular ejection fraction, a high frequency of multivessel disease, and markedly abnormal myocardial perfusion tomography, In patients with ST-segment elevation and abnormal Q waves, substantial scarring and superimposed ischemia coexist, whereas in patients without Q waves, ST-segment elevation usually denotes severe ischemia.

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Documento generato il 25/01/20 alle ore 16:35:52