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Titolo:
Diagnostic value of Tl-201 lung uptake is dependent on measurement method
Autore:
Hitzel, A; Manrique, A; Cribier, A; Vera, P;
Indirizzi:
CHU Rouen & Ctr Henri Becquerel, GIE Med Nucl, F-76000 Rouen, France CHU Rouen & Ctr Henri Becquerel Rouen France F-76000 76000 Rouen, France CHU Rouen, Hop Charles Nicolle, Serv Cardiol, Rouen, France CHU Rouen Rouen France Hop Charles Nicolle, Serv Cardiol, Rouen, France
Titolo Testata:
JOURNAL OF NUCLEAR CARDIOLOGY
fascicolo: 3, volume: 8, anno: 2001,
pagine: 332 - 338
SICI:
1071-3581(200105/06)8:3<332:DVOTLU>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY-ARTERY DISEASE; EMISSION COMPUTED-TOMOGRAPHY; LEFT-VENTRICULAR FUNCTION; HEART RATIO; MYOCARDIAL-INFARCTION; THALLIUM UPTAKE; EXERCISE; STRESS; SCINTIGRAPHY; EXTENT;
Keywords:
thallium 201; coronary artery disease; single photon emission computed tomography lung uptake;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
29
Recensione:
Indirizzi per estratti:
Indirizzo: Manrique, A CHU Rouen & Ctr Henri Becquerel, GIE Med Nucl, 1 Rue Amiens, F-76000 Rouen, France CHU Rouen & Ctr Henri Becquerel 1 Rue Amiens Rouen France F-76000
Citazione:
A. Hitzel et al., "Diagnostic value of Tl-201 lung uptake is dependent on measurement method", J NUCL CARD, 8(3), 2001, pp. 332-338

Abstract

Background, Increased lung uptake during exercise thallium 201 single photon emission computed tomography is related to left ventricular dysfunction and extent of coronary artery disease (CAD), We studied the influence of the lung region of interest (ROI), used to quantify TI-201 lung uptake, on the diagnostic value of the lung-to-heart uptake ratio(LHR) in detecting CAD with TI-201 myocardial single photon emission computed tomography. Methods and Results. We retrospectively studied 152 consecutive patients referred to our center for stress TI-201 scanning. Of these, 116 had proven multivessel CAD and 36 had either normal findings on coronary angiogram or a low likelihood (<5%) of CAD. Poststress quantitative analysis was performed from a 4 x 4-pixel ROI over the hottest myocardial region, an 8 x 8-pixel left lung ROI, an 8 x 8-pixel right lung ROI, and a manual ROI encompassing the whole right lung. The LHR was calculated for each lung ROI, Right LHR (R-LHR) provided the best interobserver and intraobserver reproducibility, R-LHR and total R-LHR values were significantly higher in patients with CAD. Only history of myocardial infarction significantly influenced the R-LHR measurement. Conclusions. The methodology of LHR measurement significantly influences the clinical contribution of TI-201 lung uptake evaluation. Optimal reproducibility and diagnostic accuracy are provided by a right lung ROI.

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Documento generato il 20/01/20 alle ore 10:26:58