Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Fast-dissolving intraoral drug delivery systems
Autore:
Liang, AC; Chen, LIH;
Indirizzi:
Lavipharm Labs Inc, E Windsor, NJ 08520 USA Lavipharm Labs Inc E Windsor NJ USA 08520 bs Inc, E Windsor, NJ 08520 USA
Titolo Testata:
EXPERT OPINION ON THERAPEUTIC PATENTS
fascicolo: 6, volume: 11, anno: 2001,
pagine: 981 - 986
SICI:
1354-3776(200106)11:6<981:FIDDS>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Keywords:
drug delivery; fast-disintegrating; fast-dissolving; film; intraoral; lyophilisation; oral; spray-dying tablets;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
7
Recensione:
Indirizzi per estratti:
Indirizzo: Liang, AC Lavipharm Labs Inc, 69 Princeton Hightstown Rd, E Windsor, NJ 08520 USA Lavipharm Labs Inc 69 Princeton Hightstown Rd E Windsor NJ USA 08520
Citazione:
A.C. Liang e L.I.H. Chen, "Fast-dissolving intraoral drug delivery systems", EXPERT OP T, 11(6), 2001, pp. 981-986

Abstract

Fast-dissolving drug delivery is rapidly gaining interest in the pharmaceutical industry. These delivery systems either dissolve or disintegrate in the mouth rapidly, without requiring any water to aid in swallowing. Such technologies offer a convenient way of dosing medications, not only to special population groups with swallowing difficulties, but also to the general population. They also impart unique product differentiation, thus enabling use as line extensions for existing commercial products. This review discusses the various technologies in recent patents used to achieve quick dissolution/dispersion in the oral cavity. They are categorised based on either processing or formulation variables. Processing techniques, such as lyophilisation, tablet moulding, sublimation and spray drying, are discussed in thisarticle. Review of the formulation techniques includes addition of sugar-based ingredients, foaming agents and disintegrants. Finally, an emerging novel dosage form, a quick-dissolving film, is discussed.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/07/20 alle ore 17:57:22