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Titolo:
Fluoxetine increases the content of neurotrophic protein S100 beta in the rat hippocampus
Autore:
Manev, R; Uz, T; Manev, H;
Indirizzi:
Univ Illinois, Dept Psychiat, Inst Psychiat, Chicago, IL 60612 USA Univ Illinois Chicago IL USA 60612 , Inst Psychiat, Chicago, IL 60612 USA
Titolo Testata:
EUROPEAN JOURNAL OF PHARMACOLOGY
fascicolo: 2-3, volume: 420, anno: 2001,
pagine: R1 - R2
SICI:
0014-2999(20010525)420:2-3<R1:FITCON>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
NEURONS;
Keywords:
neurogenesis; antidepressant; glia;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
8
Recensione:
Indirizzi per estratti:
Indirizzo: Manev, H Univ Illinois, Dept Psychiat, Inst Psychiat, 1601 W Taylor St,MC912, Chicago, IL 60612 USA Univ Illinois 1601 W Taylor St,MC912 Chicago IL USA 60612 612 USA
Citazione:
R. Manev et al., "Fluoxetine increases the content of neurotrophic protein S100 beta in the rat hippocampus", EUR J PHARM, 420(2-3), 2001, pp. R1-R2

Abstract

Recent studies indicate that a protracted daily administration of the antidepressant fluoxetine to adult rats increases cell proliferation/neurogenesis in the hippocampus. It has been hypothesized that this action of fluoxetine might be mediated by neurotrophic factors. We hypothesized that glial S100 beta could be such a factor, and using quantitative Western immunoblotting. we investigated the effect of a 21-day treatment of rats with fluoxetine (5 mg/kg). and found that fluoxetine increases the content of hippocampal S 100 beta. (C) 2001 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/12/20 alle ore 22:56:23