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Titolo:
Influence of carvedilol on the benefits of physical training in patients with moderate chronic heart failure
Autore:
Forissier, JF; Vernochet, P; Bertrand, P; Charbonnier, B; Monpere, C;
Indirizzi:
Ctr Readaptat Cardiovasc Bois Gibert, F-37510 Ballan Mire, France Ctr Readaptat Cardiovasc Bois Gibert Ballan Mire France F-37510 , France CHU Bretonneau, Lab Biostat & Informat Med, F-37044 Tours 1, France CHU Bretonneau Tours France 1 at & Informat Med, F-37044 Tours 1, France CHU Trousseau, USCI, Serv Cardiol D, F-37044 Tours 1, France CHU Trousseau Tours France 1 CI, Serv Cardiol D, F-37044 Tours 1, France
Titolo Testata:
EUROPEAN JOURNAL OF HEART FAILURE
fascicolo: 3, volume: 3, anno: 2001,
pagine: 335 - 342
SICI:
1388-9842(200106)3:3<335:IOCOTB>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
LEFT-VENTRICULAR FUNCTION; BETA-ADRENERGIC-BLOCKADE; QUALITY-OF-LIFE; MYOCARDIAL-INFARCTION; EXERCISE PROGRAM; CONTROLLED TRIAL; DOUBLE-BLIND; TERM; CAPACITY; SYMPTOMS;
Keywords:
carvedilol; beta-blocker; heart failure; physical training; cardiac rehabilitation;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: Forissier, JF Ctr Readaptat Cardiovasc Bois Gibert, F-37510 Ballan Mire, France Ctr Readaptat Cardiovasc Bois Gibert Ballan Mire France F-37510
Citazione:
J.F. Forissier et al., "Influence of carvedilol on the benefits of physical training in patients with moderate chronic heart failure", EUR J HE FA, 3(3), 2001, pp. 335-342

Abstract

Aims: To evaluate prospectively the impact of carvedilol on a short-term physical training program in stable patients with moderate chronic heart failure (CHF), and to analyze parameters predictive of improvement after training. Methods and results: Thirty-eight patients with CHF were referred for cardiac rehabilitation. Etiology was ischemic in 26 patients, dilated in 12patients and left ventricular ejection fraction was < 35%. Patients were classified into three groups: group 1 (n = 14) = ACE inhibitors, diuretics and digitalis; group 2 (n = 11)= idem group 1 + cardioselective beta-blocker; group 3 (n = 13)= idem group 1+ carvedilol. Exercise tests with VO2 measurement were performed before and after a 4-week exercise training program. Patients with carvedilol experienced a 16.6% increase in peak VO2 which wassimilar to the 13.9% increase in the group with cardioselective beta-blocker and to the 18.5% in the group without beta-blocker. Moreover non-ischemic etiology of CHF was the only parameter predictive of improvement after training (P = 0.02). Conclusions: Addition of carvedilol did not alter benefits of a short-term physical training program in patients with moderate CHF. No baseline characteristic except for etiology of CHF was predictive of a response to training. (C) 2001 European Society of Cardiology. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/01/20 alle ore 12:46:59