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Titolo:
Multiple sclerosis: recent developments in neuropathology, pathogenesis, magnetic resonance imaging studies and treatment
Autore:
Lucchinetti, C; Bruck, W; Noseworthy, J;
Indirizzi:
Mayo Clin & Mayo Fdn, Dept Neurol, Rochester, MN 55905 USA Mayo Clin & Mayo Fdn Rochester MN USA 55905 urol, Rochester, MN 55905 USA Humboldt Univ, Charite, Dept Neuropathol, Berlin, Germany Humboldt Univ Berlin Germany Charite, Dept Neuropathol, Berlin, Germany
Titolo Testata:
CURRENT OPINION IN NEUROLOGY
fascicolo: 3, volume: 14, anno: 2001,
pagine: 259 - 269
SICI:
1350-7540(200106)14:3<259:MSRDIN>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
CENTRAL-NERVOUS-SYSTEM; TUMOR-NECROSIS-FACTOR; MONOCLONAL-ANTIBODY TREATMENT; ALTERED PEPTIDE LIGAND; APPEARING WHITE-MATTER; SPIN-ECHO MRI; AXONAL INJURY; CHLAMYDIA-PNEUMONIAE; CEREBROSPINAL-FLUID; GLATIRAMER ACETATE;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
120
Recensione:
Indirizzi per estratti:
Indirizzo: Lucchinetti, C Mayo Clin & Mayo Fdn, Dept Neurol, 200 1st St SW, Rochester, MN 55905 USA Mayo Clin & Mayo Fdn 200 1st St SW Rochester MN USA 55905 A
Citazione:
C. Lucchinetti et al., "Multiple sclerosis: recent developments in neuropathology, pathogenesis, magnetic resonance imaging studies and treatment", CURR OP NEU, 14(3), 2001, pp. 259-269

Abstract

The cause of multiple sclerosis is generally considered to be entirely T cell mediated. However, recent reports of studies in a variety of animal models of inflammatory demyelinating disease, coupled with detailed pathological analysis and neuroimaging studies of multiple sclerosis patients, indicate that the events involved in the formation of the multiple sclerosis lesion may be more complicated. This complex pathogenesis is reflected in the variable response of multiple sclerosis patients to immunomodulatory therapy. Curr Opin Neurol 14:259-269. (C) 2001 Lippincott Williams & Wilkins.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 08:13:03