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Titolo:
Lamotrigine in two cases of Rett syndrome
Autore:
Kumandas, S; Casken, H; Ciftci, A; Ozturk, M; Per, H;
Indirizzi:
Erciyes Univ, Fac Med, Dept Pediat Neurol, TR-38039 Kayseri, Turkey Erciyes Univ Kayseri Turkey TR-38039 at Neurol, TR-38039 Kayseri, Turkey Erciyes Univ, Fac Med, Dept Radiol, TR-38039 Kayseri, Turkey Erciyes UnivKayseri Turkey TR-38039 pt Radiol, TR-38039 Kayseri, Turkey
Titolo Testata:
BRAIN & DEVELOPMENT
fascicolo: 4, volume: 23, anno: 2001,
pagine: 240 - 242
SICI:
0387-7604(200107)23:4<240:LITCOR>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
BROMOCRIPTINE; GIRLS;
Keywords:
Rett syndrome; lamotrigine;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Kumandas, S Erciyes Univ, Fac Med, Dept Pediat Neurol, TR-38039 Kayseri, Turkey Erciyes Univ Kayseri Turkey TR-38039 R-38039 Kayseri, Turkey
Citazione:
S. Kumandas et al., "Lamotrigine in two cases of Rett syndrome", BRAIN DEVEL, 23(4), 2001, pp. 240-242

Abstract

Rett syndrome (RS) is a particular neurodevelopmental disorder in which symptoms develop in early infancy and manifests particular symptoms at certain ages. Two girls aged 4.5 and 2.5-years-old were admitted with complaints of seizures, regression of language, psychomotor development, and autistic behavior. They had fulfilled the criteria of classic RS. Lamotrigine was used in the treatment of the convulsions. After lamotrigine therapy, the convulsions were successfully controlled and the stereotyped hand movements andautistic behaviors markedly decreased. We would like to stress that, asidefrom convulsion, abnormal signs of the syndrome such as stereotyped hand movements and autistic behaviors might also be improved with lamotrigine, but detailed and controlled studies should be performed to identify whether lamotrigine has any positive effects in RS. (C) 2001 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/20 alle ore 10:16:45