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Titolo:
Introduction to, and classification of, the systemic vasculitides
Autore:
Luqmani, RA; Robinson, H;
Indirizzi:
Western Gen Hosp, Dept Rheumatol, Edinburgh EH4 2XU, Midlothian, Scotland Western Gen Hosp Edinburgh Midlothian Scotland EH4 2XU dlothian, Scotland
Titolo Testata:
BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY
fascicolo: 2, volume: 15, anno: 2001,
pagine: 187 - 202
SICI:
1521-6942(200106)15:2<187:ITACOT>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
RHEUMATOLOGY 1990 CRITERIA; CHURG-STRAUSS-SYNDROME; GIANT-CELL ARTERITIS; HEPATITIS-B VIRUS; WEGENERS-GRANULOMATOSIS; POLYARTERITIS-NODOSA; INCREASING INCIDENCE; 5-YEAR PERIOD; DISEASE; NOMENCLATURE;
Keywords:
vasculitis; Wegener's granulomatosis; Churg-Strauss syndrome; Kawasaki disease; Takayasu's arteritis; giant-cell arteritis; anti-neutrophil cytoplasmic antibody; hepatitis C; hepatitis B; epidemiology; classification; cryoglobulinaemia; Henoch Schonlein purpura; polyarteritis nodosa; microscopic polyangiitis;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
69
Recensione:
Indirizzi per estratti:
Indirizzo: Luqmani, RA Western Gen Hosp, Dept Rheumatol, Crewe Rd, Edinburgh EH4 2XU,Midlothian,Scotland Western Gen Hosp Crewe Rd Edinburgh Midlothian Scotland EH4 2XU
Citazione:
R.A. Luqmani e H. Robinson, "Introduction to, and classification of, the systemic vasculitides", BEST PR R C, 15(2), 2001, pp. 187-202

Abstract

This overview serves as an introduction to the systemic vasculitides, which are a group of heterogeneous disorders sharing a common pathophysiological mechanism leading to blood vessel inflammation and tissue necrosis. Our lack of understanding of the aetiology for most forms of vasculitis has resulted in the development of a classification system, which is primarily based on vessel size. Such a system assists in the grouping together of similarconditions for the purposes of multi-centre studies. Difficulties arise inclassification of the vasculitides due to considerable overlap of clinico-pathological features; for example, microscopic polyangiitis (MPA), Wegener's granulomatosis (WG) and Churg-Strauss syndrome (CSS) may all cause the identical renal lesion of necrotizing glomerulonephritis. The rationale for treatment often depends on the type of vasculitis and on the extent of organ involvement. Treatment may be similar for different types of disease. Thelack of validated diagnostic criteria has, however, resulted in the application of classification criteria in their place, and has highlighted the limited usefulness of classification criteria in clinical practice. Classification systems should assist in the determination of therapy and prediction of outcomes, but have many limitations, which are discussed further in thisreview.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 12:25:40