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Titolo:
Loss of virulence by heterophil-adapted Salmonella pullorum
Autore:
Kramer, TT; Hirl, M;
Indirizzi:
Iowa State Univ, Coll Vet Med, Vet Med Res Inst, Ames, IA 50011 USA Iowa State Univ Ames IA USA 50011 d, Vet Med Res Inst, Ames, IA 50011 USA
Titolo Testata:
AVIAN DISEASES
fascicolo: 2, volume: 45, anno: 2001,
pagine: 452 - 455
SICI:
0005-2086(200104/06)45:2<452:LOVBHS>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
CHOLERAESUIS; ENTERITIDIS;
Keywords:
Salmonella pullorum; heterophil adaptation; avirulence; day-old chicks;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Citazioni:
7
Recensione:
Indirizzi per estratti:
Indirizzo: Kramer, TT 3673 Point Dr, Ft Collins, CO 80524 USA 3673 Point Dr Ft Collins CO USA 80524 Ft Collins, CO 80524 USA
Citazione:
T.T. Kramer e M. Hirl, "Loss of virulence by heterophil-adapted Salmonella pullorum", AVIAN DIS, 45(2), 2001, pp. 452-455

Abstract

We report that reduction of virulence for day-old chicks was achieved after eight-times-repeated heterophil passage of Salmonella pullorum (SP). The virulent source strain SP-V caused 64% mortality and 83% internal organ as well as 83% cecal colonization 10 days after administration of 10(7) colony-forming units (CFU) to day-old chicks. Eighe-times-repeated passage of SP in heterophils resulted in attenuated strain SP-A that was nonlethal and reduced colonization of internal organs from 89% for SP-V strain to 4.3% for SP-A strain 10 days after administration of 10(7) or 10(8) CFU to day-old chicks. Cecal colonization was reduced from 89% for SP-V strain to 0 for SP-A strain 10 days after administration of 107 or 108 CFU to day-old chicks.

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Documento generato il 06/04/20 alle ore 19:06:18